Factors That Determine the Responses to Meal Ingestion: Meal Composition
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Change in digestive well-being measured after the test meal
研究概览
简要总结
Aim: to determine to what extent meal composition influences postprandial sensations independently of palatability. The postprandial responses to a low-fat (240 Kcal) versus a high-fat (275 Kcal) test meal (150 g humus) with the same physical and organoleptic characteristics (taste, smell, colour, texture, consistency, temperature) will be studied on a cross-over design. The responses to the meals will be tested on 2 different days. Participants (12 non-obese healthy men) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 3 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Perception will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •non-obese
排除标准
- •history of gastrointestinal symptoms
- •prior obesity
- •use of medications
- •history of anosmia and ageusia
- •current dieting
- •alcohol abuse
- •psychological disorders
- •eating disorders
研究组 & 干预措施
High-fat meal
干预措施: High-fat meal (Other)
Low-fat meal
干预措施: Low-fat meal (Other)
结局指标
主要结局
Change in digestive well-being measured after the test meal
时间窗: 1 day
Change in average well-being measured by 10 score scales at the end of the test meal.
次要结局
- Change in satiety measured after the test meal(1 day)
- Change in mood measured after the test meal(1 day)
- Change in fullness sensation measured after the test meal(1 day)
- Change in abdominal discomfort/pain sensation measured after the test meal(1 day)
