Outcomes of Short-term Perioperative Thromboprophylaxis After Gastrointestinal Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 89
- 试验地点
- 2
- 主要终点
- The incidence of thromboembolic events by radiological assessment
研究概览
简要总结
Major abdominal surgery for cancer is major risk factor for thromboembolism. Patients who undergo major abdominal surgery are prone to develop venous thromboembolism, both in the early postoperative period and after hospital discharger. There are strong recommendations in the international guidelines in favor to pharmacological thromboprophylaxis. Thus there is no consensus dor the duration of the prophylaxis. There are authors that suggest extended prophylaxis up to 4 week after surgery. On the other hand, there are prospective randomized trials that inpatient (short-term up to 7-10 days) prophylaxis is adequate.
详细描述
This is a retrospective cohort study with 89 patients who underwent major abdominal surgery for colorectal and gastric cancer. All patients received short term prophylaxis (during hospital stay only) rather than extended prophylaxis (4 weeks). All participants received duplex ultrasound in the study period for the diagnosis of deep vein thrombosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Older than 18
- •Major abdominal surgery gor colorectal or gastric cancer
- •Caprini Risk score less than 9
- •No history of anticoagulant treatment
- •Thromboprophylaxis during hospital stay only
排除标准
- •Younger than 18
- •Caprini Risk score 9 and above
- •History of anticogulants
- •Not reachable by phone etc
结局指标
主要结局
The incidence of thromboembolic events by radiological assessment
时间窗: 3 years follow up
All patients in the cohort received short time prophylaxis for deep vein thrombosis instead of prolonged duration. All patients will be assessed with ultrasound.
次要结局
- Rate of predisposing factors of the patients(3 years follow up)
研究者
Nuray COLAPKULU
Surgical Resident (Research Assistant) at General Surgery
Istanbul Medeniyet University