ISRCTN70120536已完成未知
Characterisation of the peptide and cellular constituents of cerebrospinal fluid implicated in the chronicity of neuropathic pain in vivo and its response to treatment with amitriptyline and neuromodulation
St James's Hospital / Trinity College Dublin0 个研究点目标入组 20 人开始时间: 2017年9月12日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
2021 Results article in https://doi.org/10.1016/j.bbih.2020.100184 (added 11/10/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Amitriptyline study:
- •1. Patients aged 20 – 65 years with lumbar radicular pain
- •2. Clinical and radiological evidence of one nerve root and/or dermatome affected
- •Neuromodulation study:
- •1. Patients aged 20 – 65 years with FBSS or CRPS who have been implanted with a spinal cord stimulator
排除标准
- •Amitriptyline study:
- •1. Patient refusal
- •2. Anticoagulant medication
- •3. Infection
- •4. Pregnancy
- •5. Breastfeeding
- •6. Corticosteroid therapy
- •8. Psychiatric history
- •9. History of ischaemic heart disease
- •10. Arrhythmia
- •11. Heart block
- •12. Cerebral impairment
- •13. Current anti-neuropathic medication
- •14. Biologic medication
- •Neuromodulation study:
- •1. Patient refusal
- •2. Anticoagulant medication
- •3. Infection
- •4. Pregnancy
- •5. Breastfeeding
- •6. Corticosteroid therapy
- •8. Psychiatric history
- •9. Cerebral impairment
- •10. Biologic medication
研究者
相似试验
进行中（未招募）
不适用
nderstanding the genetic causes and clinical aspects of being born with a mutation in the TP53 gene in SwedeGermline TP53 mutation carriersGenetic DiseasesISRCTN13103571Stockholms Läns Landsting60
尚未招募
1 期
Peptidomics Profile Characterization and Diagnostic Model Construction of Heart FailureHeart FailureITMCTR2000003344Hunan University of Chinese Medicine
招募中
4 期
Evaluation of the role of new remineralizing material in prevention of tooth decay in head and neck cancer patients after radiation therapyCTRI/2021/02/031001Indian Council of Medical Research
已完成
1 期
Phase I study of peptides derived from novel cancer antigen using with Gemcitabine for advanced pancreatic cancerJPRN-UMIN000007504YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE Department of Digestive Surgery and Surgical Oncology18
尚未招募
不适用
An observational study of the correlation between stem/progenitor cell levels and wound healing in diabetic foot ulcers.ACTRN12616000442404ational Institutes of Health (NIH),800