Improving Real-world Function for Persons with Schizophrenia (ImproFunc): a Single-case Experimental Design
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 27
- 主要终点
- PRPP assessment
研究概览
简要总结
Existing treatment for individuals with psychosis primarily targets positive symptoms but has only modest effects on cognition and negative symptoms. Cognitive strategy training shows promising effects in reducing negative symptoms and increasing activity initiation in individuals with schizophrenia.
This project aims to investigate the effect of the Perceive, Recall, Plan and Perform (PRPP) intervention in promoting effective use of cognitive strategies for adults with schizophrenia in performing their daily activities. Twenty-seven individuals with schizophrenia will be recruited from Sykehuset Innlandet (Innlandet Hospital Trust) and assessed using PRPP prior to an eight-session PRPP intervention. Re-assessment will be conducted after the intervention, as well as at 3 and 6 months, to evaluate the long-term effects of the intervention. A single-case design will be used to investigate the intervention's effects. The primary outcome measure will be the PRPP assessment, and the secondary outcome measure will be the Goal Attainment Scale (GAS). Generalization measures will be used to evaluate whether there are relevant changes beyond the primary and secondary goals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
盲法说明
We plan for the assessor to be blinded when scoring the PRPP assessment. Therefore, one occupational therapist will conduct the assessments before and after the intervention, and another will provide the intervention for the participants. Additionally, to monitor observer drift , a third occupational therapist (the PhD candidate and the main supervisor) will be blinded to the phases and score 20 % of the PRPP assessments.
入排标准
- 年龄范围
- 18 Years 至 59 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DSM-5 diagnosis of schizophrenia, understand and speak Norwegian, live in their own community context, but are patients in Sykehuset Innlandet ( Innlandet Hospital Trust), either as outpatients or on discharge from inpatient care, a subjective experience of functional impairment and/or cognitive difficulties identified in an initial interview, and a stable state without any major medication change for at least two months before inclusion
排除标准
- •Major physical disability, a current substance abuse problem, and cognitive deficits of organic origin or mental retardation
结局指标
主要结局
PRPP assessment
时间窗: Assesments just after the intervention, as well as at 3 and 6 months
Effective use of cognitive strategies in performing their daily activities
次要结局
- Goal Attainment Scale(Assesments just after the intervention, as well as at 3 and 6 months)
- Health of the Nation Outcome Scale(Assesments just after the intervention, as well as at 3 and 6 months)
- Social Functioning Scale(Assesments just after the intervention, as well as at 3 and 6 months)
- Questionnaire about the Process of Recovery(Assesments just after the intervention, as well as at 3 and 6 months)