ACTRN12606000155594进行中（未招募）未知
A continuous positive airway pressure (CPAP) weaning trial to determine the most efficient method in weaning babies less than 30 weeks gestational age OFF CPAP.
Dr David Todd0 个研究点目标入组 200 人开始时间: 2006年5月3日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- ot stated 至 30 Weeks（—）
- 性别
- All
入选标准
- •1.All babies <30 weeks gestational age 2.On CPAP for >24 hours 3.Babies either extubated to CPAP or as a primary treatment for respiratory distress Criteria for commencing weaning: Babies must have all of the following for the past 12 hours:- 1.CPAP <6 cm H2O 2.Oxygen requirement less than 26% and not increasing 3.RR less than 60 4.No significant chest recession 5.Less than 3 episodes of mild self reverting apnoeas and/or bradycardias and/or desaturations in 1 hour for the previous 6 hours 6.Average saturation above 87% most of the time and/or transcutaneous (TcPO2)/arterial PaO2 >50 mm Hg. 7.Tolerates nose rests well during nursing cares 8.Not treated for patent ductus arteriosus (PDA) or sepsis Criteria for failed trial OFF” at least 2 of the following:- 1.Increase work of breathing (Intercostal recession and accessory muscles contributing for respiration) with RR >75 for >1 hour 2.Increased apnoeas and/or bradycardias and/or desaturations >2 in previous 1 hour 3.Major apnoea or bradycardia requiring more sustained stimulation/ resuscitation 4.Increased O2 requirement >25% with average saturation <85% and/or TcPO2/PaO2 <45mmHg 5.pH of <7.2 6.PaCO2 of > 65 mmHg. The babies will be put back on CPAP if failed trial OFF” CPAP. If a baby has a major apnoea and/or bradycardia requiring resuscitation they may require intubation and ventilation.
排除标准
- •1. If congenital respiratory abnormality including central and anatomical.
研究者
相似试验
尚未招募
不适用
Comparing standard therapy and use of high pressure oxygen in children with Bronchiolitis .CTRI/2020/06/026071Dr S Muralikrishna
进行中（未招募）
不适用
Should very premature babies be treated at birth with intubation and ventilation or just a continuous positive pressure into the nose?Very premature infantsChronic lung disease (CLD)Reproductive Health and Childbirth - Childbirth and postnatal careRespiratory - Other respiratory disorders / diseasesACTRN12606000258550Women's and Children's Research Foundation600
已完成
不适用
Do Treatment Interventions for Obstructive Sleep Apnoea Reduce Depressive Symptoms in Patients with Comorbid Depression?DepressionObstructive Sleep ApnoeaRespiratory - Sleep apnoeaMental Health - DepressionACTRN12614000013662Royal Melbourne Institute of Technology132
已完成
3 期
Continuous Positive Airway Pressure (CPAP) for the treatment of severe respiratory distress in the pre-hospital settingHeart failureSevere respiratory distress.Respiratory - Other respiratory disorders / diseasesCardiovascular - Other cardiovascular diseasesACTRN12615001180505Curtin University708
进行中（未招募）
不适用
CPAP- Is Pressure Important? A randomised, double blinded, crossover, pilot trial on Continuous Positive Airway Pressure (CPAP), and it's effects upon apnoea, bradycardia and desaturation episodes, and oxygen requirement in preterm infants with respiratory distress syndrome.Respiratory Distress SyndromeReproductive Health and Childbirth - Complications of newbornACTRN12609000137291Anna Tottman10