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临床试验/NCT03911635
NCT03911635Unknown不适用

Applying of Urethral Advancement, Glanuloplasty and Preputioplasty Technique for More Proximal Degrees of Hypospadias. Selective Criteria and a Modified Technique

Assiut University0 个研究点目标入组 75 人开始时间: 2020年4月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
75
主要终点
Assessment of the patient immediately after removal of the catheter at the 7th day and after 3 weeks

研究概览

简要总结

Hypospadias is a condition in which the location of the urethral meatus is on the ventral aspect of the penis.

Hypospadias is the most common congenital anomaly of urogenital organs in boys, with an incidence of approximately 1 in 250 newborns. Recently, case selection has been advised to avoid possible complications and limitations [1]. The meatal advancement and glanuloplasty (MAGPI) procedure was first described in 1981 for the repair of distal hypospadias. An excellent surgical result requires careful case selection, avoiding cases with thin or rigid ventral para-meatal skin or a meatus too proximal or too wide. The glans wrap to support the advanced ventral urethral wall requires a solid tissue approximation in two layers to prevent regression of the meatus. Meatal stenosis can be avoided by assuring an adequate dorsal Heineke- Mikulicz tissue rearrangement and making an incision from within the urethral meatus well distally into the urethral groove. . The overall success rate with the MAGPI procedure suggests that it should continue to be used in the repair of distal hypospadias [2]. The advantage of Urethral advancement, Glanuloplasty, and Preputioplasty " URAGPI" versus MAGPI Is that A) Applicability to almost any type of distal hypospadias regardless of the severity of glanular ventriflexion.

B) Normal appearance of the penis. C) Good functional results.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
1 Year 至 12 Years(Child)
性别
Male
接受健康志愿者

入选标准

  • All patient with hypospadias from 1 to 12 years with penile selection according to Wang YN et. al

排除标准

  • circumcised patients
  • sever degrees of chordae
  • previous surgical repair
  • meatal stenosis

结局指标

主要结局

Assessment of the patient immediately after removal of the catheter at the 7th day and after 3 weeks

时间窗: 3 weeks

evaluation according to "Hypospadias Objective Penile Evaluation Score"

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ali Ahmed

Principal Investigator

Assiut University

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