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临床试验/NCT04941092
NCT04941092已完成不适用

Clinical Outcomes and Characteristics of Critically Ill Patients With Influenza and COVID-19 Induced ARDS: a Retrospective, Matched Cohort Study

Central Hospital, Nancy, France1 个研究点 分布在 1 个国家目标入组 157 人开始时间: 2021年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
157
试验地点
1
主要终点
mortality

研究概览

简要总结

Since the beginning of the SARS CoV 2 pandemia, the SARS CoV 2 was frequently compared with the seasonal influenza virus. However, few studies compared patients presenting acute respiratory distress syndrome (ARDS) induced by these viruses, with results being discordant. Our study means to compare mortality and morbidity of patients hospitalized in an intensive care unit (ICU) with ARDS induced by SARS CoV-2 and seasonal influenza.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients hospitalized in ICU
  • under mechanical ventilation
  • presenting an ARDS according to the Berlin definition
  • induced by either influenza or SARS CoV 2

排除标准

  • pregnant women
  • mechanical ventilation>48 hours before admission

结局指标

主要结局

mortality

时间窗: at 28 days

次要结局

  • length of mechanical ventilation(at 28 days)
  • length of stay in ICU(at 28 days)
  • length of vasopressors(at 28 days)
  • length of extrarenal epuration(at 28 days)
  • amount of drugs for sedation(at 28 days)

研究者

发起方
Central Hospital, Nancy, France
申办方类型
Other
责任方
Principal Investigator
主要研究者

Lev VOLKOV

Dr

Central Hospital, Nancy, France

研究点 (1)

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