NCT00353795已完成不适用
Coronary Atherosclerosis Evaluation by Arterial Wall MRI
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 179
- 试验地点
- 4
- 主要终点
- Mean Coronary Wall Thickness
研究概览
简要总结
The overall goal of this study is to use MRI to:
- Examine the relationship between known risk factors for cardiovascular disease and coronary artery wall thickness;
- Examine the relationship between coronary artery wall thickness and other markers of subclinical coronary atherosclerosis, such as carotid wall thickness and coronary calcium scores; and,
- Examine the feasibility of measuring the progression of coronary artery wall thickness over time in a subset of participants.
详细描述
Each enrolled participant will undergo MR Imaging of the coronary arteries in conjunction with their routine MESA follow-up visit. The MRI will last approximately 45-60 minutes
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Prior enrollment in the MESA Study at the Hopkins MESA Field Center or the Northwestern University MESA Field Center
- •Male or Female adult equal to or older than 45 years of age
- •Willing/able to provide informed consent
排除标准
- •Any known contraindications to MRI (i.e. severe claustrophobia, pacemaker, etc.)
- •Metal in the eyes
结局指标
主要结局
Mean Coronary Wall Thickness
时间窗: n/a (cross sectional analysis)
Average thickness of the wall of the left anterior descending, right and left main coronary artery measured by magnetic resonance imaging (MRI).
次要结局
未报告次要终点
研究者
研究点 (4)
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