NCT00133380已完成2 期
PPAR Alpha (LY518674): A Phase 2 Study of the Combinatorial Effect of LY518674 and Atorvastatin in Subjects With Hypercholesterolemia
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 29
- 主要终点
- Effects on "bad" cholesterol, LDL-C, after 12 weeks
研究概览
简要总结
The purposes of this study are to determine:
- The safety of the study medication and any side effects that might be associated with it
- Whether the study medication can help patients with high levels of "bad" cholesterol (low-density lipoprotein-cholesterol [LDL-C]), alone or in combination with additional study medication
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men and women between 18 and 80 years of age
- •People with abnormal cholesterol levels
排除标准
- •People with diabetes
- •People whose blood pressure >160/95 mm Hg, on or off blood pressure medicine
- •People who have had frequent chest pain or unstable angina, a heart attack or a heart procedure including stent placement, within the past 3 months
结局指标
主要结局
Effects on "bad" cholesterol, LDL-C, after 12 weeks
次要结局
- Evaluate safety after 12 weeks
- Effects on other lipids and biomarkers associated with atherosclerosis after 12 weeks
- Evaluate interaction of the 2 different study medications
研究者
研究点 (29)
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