Project of Health Promotion and Management for Hepatitis B Carriers in NTU Campus
试验速览
- 阶段
- 不适用
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Reduction of relative serum HBV DNA levels
研究概览
简要总结
The investigators propose a project of preventive medicine with concern of local context in Taiwan. The target population includes all staff and faculty members, students, and alumni of a university in Northern Taiwan, with chronic hepatitis B infection. The intervention of this project includes standardized lectures, sports courses, nutrition courses, and an information platform. The investigators will evaluate the efficacy after the intervention, like the reduction of hepatitis B viral load and the associated anthropometric parameters. The results of this project will be initially served as a pilot study for this cohort, and applicated as a promising basis for health promotion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants were recruited from students, alumni, faculty and staff members with chronic HBV infection (positive HBsAg serostatus ≥6 months) in a university of northern Taiwan from August 1, 2009 to July 01,
- •Only participants aged 18 and older were included.
排除标准
- •Excluded were:
- •(a) those who had been diagnosed as chronic liver diseases like chronic hepatitis C infection (Anti-HCV (+)), autoimmune hepatitis, Wilson disease, alcoholic liver diseases, drug-related hepatitis, decompensated liver diseases, cirrhosis, or malignant hepatic tumors;
- •(b) those who had undergone liver transplantation or major operations for liver except cholecystectomy;
- •(c) men who consumed more than 30 gram of alcohol per week or women who consumed more than 20 gram of alcohol per week;
- •(d) women who were pregnant;
- •(e) those who had current medications for any types of chronic diseases except for hyperglycemia, elevated blood pressure, or dyslipidemia within six months.
研究组 & 干预措施
Lifestyle conseling
干预措施: standardized exercise program and dietary counseling (Behavioral)
结局指标
主要结局
Reduction of relative serum HBV DNA levels
时间窗: three months
次要结局
- anthropometric index(three months)