ACTRN12621000144819已完成未知
A randomised controlled study investigating the effects of two different 12-week aerobic exercise training interventions on cardiorespiratory fitness, brain blood flow, brain volume, and cognitive function in middle-aged adults
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 70
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 45 Years 至 65 Years（—）
- 性别
- All
入选标准
- •Aged 45-65
- •- Able to participate in 36 exercise sessions over 12 weeks
- •- Normal cognition on screening
- •- BMI of 18 to 40
- •- Sign off from doctor to participate in the study
排除标准
- •- Involved in regular exercise training in the previous 6 months
- •- Significant medical co-morbidities precluding participation in an exercise intervention (e.g., severe cardiac disease)
- •- Contraindications to have MRI
- •- Mild cognitive impairment on screening
- •- Recent diagnosis (14 days), close contact, or symptomatic of COVID-19
- •- Underweight or morbidly obese (BMI < 18 or > 40)
- •- History of any serious traumatic brain injury (e.g., ICU stay, rehab required, and/or a prolonged period of unconsciousness).
- •- High blood pressure at rest (over 160/100 mmHg)
- •- Current or ex-smoker (last 12 months)
- •- Any blood disorders or brain tumours
- •- Started any new medications (e.g., hormone replacement therapy) in the last 3 months
研究者
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