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临床试验/NCT06806748
NCT06806748尚未招募不适用

Observational Study of Recovery of Gait in Sub-acute Hemiplegic Stroke Patients

University of Strathclyde0 个研究点目标入组 36 人开始时间: 2025年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
36
主要终点
Gait symmetry

研究概览

简要总结

The purpose of this observational study is to track the recovery of stance duration symmetry during the first 6 months after stroke using wearable sensors and explore the influence of stroke specific factors (time since stroke, stroke type, location and paretic side).

详细描述

Gait impairments can limit the ability to perform daily activities and increase the risk of falls in stroke survivors. Although rehabilitation improves walking in people with stroke, it is unclear whether the improvement relies on compensatory strategies or can be further improved to achieve normal or closer to normal performance.

Stance duration symmetry is an ideal measure of gait recovery in stroke survivors as it indicates the paretic sides capacity to control body weight and maintain balance during walking. Measuring stance duration symmetry may, therefore, be useful for monitoring gait recovery and could be considered as one of key goals in stroke rehabilitation.

Understanding the mechanisms of gait recovery in people with stroke is, therefore, essential for designing treatment program, setting realistic goals and appropriate timing for promoted intervention according to their stroke characteristics.

Our plan is to track changes in the symmetry of stance duration of hemiplegic patients during the first 6 months after stroke attached at the following time points: 1) at recruitment (within 2 weeks after of stroke), 2) 4th weeks (1 month) after stroke, 3) 12th weeks (3 months) after stroke, and 4) 26th weeks (6 months) after stroke. Two wearable accelerometers (the ActivPAL4+, PAL technology, Glasgow, UK) directly to the skin of both anterior thighs using sticky pads for 4 days (24 hours) period. Demographic (age and gender) and relevant clinical data (10-meter walk test, Modified Rivermead Mobility Index (RMI), stroke type, paretic side) will also be recorded as factors to explain gait symmetry.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • aged 18 or older
  • diagnosis of a first occurrence of stroke by consultant stroke physician
  • Medically stable
  • referred for rehabilitation
  • functional ambulatory category of 1 and over

排除标准

  • acute skin condition
  • transient ischemic stroke
  • comorbidities that may interfere with walking function, such as Parkinson's disease or lower limb amputation
  • severe communication impairments or delirium

结局指标

主要结局

Gait symmetry

时间窗: From enrollment to 6 months

Gait symmetry will be measured from the signals produced by two thigh mounted inertial motion units. The variable of prime interest is the difference in stance duration between the hemiplegic and non-hemiplegic sides

次要结局

  • Rivermead Mobility Index(From enrollment to 6 months)
  • Ten meter walk test(From enrollment to 6 months)

研究者

申办方类型
Other
责任方
Sponsor

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