跳至主要内容
临床试验/NCT05678608
NCT05678608招募中不适用

Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Sohag University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2022年12月13日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
20
试验地点
1
主要终点
american spinal injury association scale

研究概览

简要总结

Primary spinal cord tumors constitute 2-4% of all central nervous system neoplasms; they are classfied as extradural, intradural extramedullary (IDEM: 65%), and intramedullary The most commonly seen IDEM tumors are schwannomas, neurofibromas, and meningiomas. [1] The less frequently encountered IDEM tumors include ependymomas, lipomas, hemangiomas, metastatic deposits, paragangliomas, nerve sheath myxomas, and vascular tumors.[2] Spinal cord tumors can cause different signs and symptoms, especially as tumors grow. The tumors may affect spinal cord or the nerve roots, blood vessels or bones of spine. Signs and symptoms may include: Pain at the site of the tumor due to tumor growth Back pain, often radiating to other parts of body Feeling less sensitive to pain, heat and cold Loss of bowel or bladder function Difficulty walking, muscle weakness .

MRI is the investigation of choice,however other investigation such CT or X ray are important to ensure stability of the vertebral column and the optimal management is gross total excision for symptomatic lesions.[3,4] Over the years, there has been no significant change in the clinical symptoms and pathology of IDEM tumors. However, there have been dramatic improvements in the diagnosis and treatment with the advances of radiological and surgical techniques. Despite advances in operative techniques and neuroimaging, the morbidity associated with the resection of IDEM tumors continues to be significant [5,6].

Here, we examined the surgical outcomes of 20 patients with IDEM spinal cord tumors operated in Neurosurgery department at Sohag university Hospital

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients with intradural extramedullary lesion in dorsolumber region

排除标准

  • previous history of spinal surgery
  • unfit medical patients
  • multiple level affection
  • associated cervical lesion
  • unstable segment

结局指标

主要结局

american spinal injury association scale

时间窗: 6 months

grading of impairment for motor and sensory functions grade A for complete sensory and motor loss grade E for normal motor and sensory

visual analogue pain scale

时间窗: 6 months

pain scale from zero to ten depend on severity of pain,

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed AHmed Kassem

demonstrator at neurosurgery department

Sohag University

研究点 (1)

Loading locations...

相似试验