Psychophysiological effects of magnesium supplementation in women in the fertile period

The objective of this clinical trial was to investigate the psychophysiological effects of nutraceuticals in college students using a model of experimental induction of anxiety, through the assessment of physiological and psychological parameters. The study was the clinical trial experimental, kind of randomized controlled . It was composed of sixty students, females, which were placed in one of four experimental groups. The human anxiety was induced by Test Simulated Public Speaking (TSFP) and was assessed by physiological parameters (Systemic Blood Pressure, Heart Rate, Temperature of Extremity, Electrical Skin Conductance) and psychological parameters (State-Trait Anxiety Inventory). Comparing the groups all showed changes that confirmed the efficacy of TSFP in experimentally induce anxiety. The diastolic blood pressure was higher in group B6 compared to the control group (P <0.05), there was still a decrease in conductance B6 group (P <0.01) and Magnesium + B6 group (P <0, 05) compared to the control group. In the final moment of the TSFP the conductance was lower in group B6 compared with group controls (P <0.05). The STAI-T showed that the college students had moderate levels of anxiety (STAI-T> 40 points). In the comparison between groups was observed that all individuals of the respective groups already started the test with a moderate degree of anxiety (STAI-E 40 - 60 points). There was a decrease in the score of the STAI-E in both groups at the end where they began to be classified with low levels of anxiety (STAI-E <40 points), but this decrease was not statistically significant (P> 0.05 ). The use of magnesium and vitamin B6 in the concentration of 200 mg did not show enough results to prove their efficacy in controlling symptoms of anxiety. The Test of Simulated Public Speaking, using nutraceuticals was effective in inducing experimental anxiety which allows further investigations are undertaken and which can produce new developments and indications for the use of vitamins and minerals in the clinical treatment of anxiety.