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临床试验/CTRI/2025/08/092834
CTRI/2025/08/092834尚未招募不适用

Evaluation of predictive value of newer scoring system SHUDE SCORE for chronic endometritis in women with previous reproductive failure undergoing IVF treatment.

Dr Shuchi JAIN1 个研究点 分布在 1 个国家目标入组 125 人开始时间: 2025年8月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
125
试验地点
1
主要终点
Effectiveness of SHUDE score in predicting chronic endometritis compared to the gold standard i.e CD 138 levels determined by immunohistiochemistry.

研究概览

简要总结

Brief Summary

In women with infertility development of scoring system for pathologies like endometriosis has aided in judging the severity and prognosticating pregnancy outcome in these women. In a community setting in India, where feasibility and cost involvement of doing CD 138 levels by immunohistiochemistry is not possible development off scoring system based on clinical and hysteroscopic findings will help in diagnosing chronic endometritis. Development of such a score would also help in counselling women regarding cumulative pregnancy rate. The scoring system established by this study including clinical and hysteroscopy criteria will have predictive value for the diagnosis of CE; it is hoped that the use of this system can reduce interobserver variability. The availability of this prediction model provides a counselling tool for physicians to IVF clients which ensures improved confidences level and reduced disappointments from failures in successful implantation and embryonic transfer including its associated financial costs and health risks.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 45.00 Year(s)(—)
性别
Female

入选标准

  • (1) a history of previous implantation failure after IVF or previous pregnancy loss.
  • (2) normal hysterosalpingography (3) normal chromosomal karyotype (4) normal thyroid function test and prolactin.

排除标准

  • Unexplained uterine bleeding History of antibiotic treatment in the month preceding the biopsy, Uterine malformation, Cavity -deforming submucosal myoma If patients are smokers or alcohol consumers Do not wish to continue with this study.

结局指标

主要结局

Effectiveness of SHUDE score in predicting chronic endometritis compared to the gold standard i.e CD 138 levels determined by immunohistiochemistry.

时间窗: 1 YEAR

次要结局

未报告次要终点

研究者

发起方
Dr Shuchi JAIN
申办方类型
Other [self financed]
责任方
Principal Investigator
主要研究者

SHUCHI JAIN

Mahatma Gandhi Institute of Medical Sciences, Sevagram

研究点 (1)

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