Parasite Clearance of Two Commonly Administered Artemisinin-Based Combination Therapies in Under-Five Children With Uncomplicated Malaria at Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife.

Ahmed Abdulakeem0 个研究点目标入组 122 人开始时间: 2020年6月15日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•(i)All patients between the age of 6 month and 59 months with signs and symptoms of acute uncomplicated malaria.
•(ii)Axillary temperature =37.5 ºC or history of fever during the past 24 hr.
•(iii)Ability to swallow oral medication.
•(iv)Microscopically confirmed asexual forms of P. falciparum with parasite density count of between 2000 and 200 000 parasites / µl.
•(v)Willingness of the parent/guardian to comply with protocol as regards the study visit schedule.

•(i)Those having symptoms and signs of severe falciparum malaria.
•(ii)A febrile condition due to diseases other than malaria e.g. measles, acute lower respiratory tract infection.
•(iii)Patients having severe malnutrition.
•(iv) Patients with sickle cell anaemia.
•(v)History of use of medication such as erythromycin, azithromycin, clindamycin and Septrin that might interfere with antimalarial pharmacokinetics.
•(vi)History of hypersensitivity to any of the study drugs will be excluded from the study.

发起方

Ahmed Abdulakeem