NCT01757886Unknown不适用
inflAmmatory maRkers in Blood and Thrombus Aspirated From Patients With acutE myocaRdial Infarction With St-segment elevAtion
Fundación Canaria Rafael Clavijo para la Investigación Biomédica1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年11月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The primary objective of the study is to find out whether there is an association between certain inflammatory markers in blood and intracoronary thrombus and whether these markers are associated with the composite of all-cause mortality
研究概览
简要总结
The prognostic value of inflammatory markers in acute coronary syndrome has been extensively demonstrated, however it is still unknown whether there is an association between circulating and local (thrombus) inflammatory molecules, and the subset of molecules that provide better prognostic information in patients with ST-elevation acute coronary syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •They include patients of both sexes, without limits of age, with a diagnosis of STEMI within 12 hours after the beginning of symptoms. ST-elevation myocardial infarction was defined in the presence of symptoms consistent, persistent elevation (> 20 min) ST segment ≥ 1 mm in at least two contiguous leads or in the presence of left bundle branch block presumably new onset and cardiac troponin I elevation
排除标准
- •Injury significant common core of left coronary artery (stenosis greater than or equal to 50% of the vessel lumen).
- •Pre-Fibrinolysis percutaneous coronary intervention.
- •Previous coronary bypass surgery.
- •Thyrotoxicosis.
- •Having an inflammatory systemic or local inflammatory process.
- •Malignant neoplasm.
- •Any disease that seriously compromise the prognosis and / or systemic inflammatory response generated.
- •No thrombotic material obtained in the thrombus or insufficient for performing biochemical determinations.
结局指标
主要结局
The primary objective of the study is to find out whether there is an association between certain inflammatory markers in blood and intracoronary thrombus and whether these markers are associated with the composite of all-cause mortality
时间窗: one year
次要结局
未报告次要终点
研究者
Enrique Quintero
Alberto Dominguez Rodriguez
Fundación Canaria Rafael Clavijo para la Investigación Biomédica
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Association Between Inflammatory Biomarkers in CVD Patients on Empagliflozin.Heart FailureStable AnginaNCT05911724Damanhour University180
Unknown
不适用
Coronary Artery Disease: a Case- Control StudyCoronary Artery DiseaseNCT03075566Nadia Bouzidi, PhD517
Unknown
不适用
CCTA Coronary Hemodynamics, Systemic Inflammation and Vulnerable Plaques (COHESIVE)Systemic Inflammatory ResponseAtherosclerosisChronic Coronary SyndromeCoronary Artery DiseaseNCT05488249Cardio Med Medical Center100
终止
不适用
Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain)Acute Respiratory Distress SyndromeNCT02003326Centre Hospitalier Universitaire de Nice6
招募中
不适用
Circulating Markers for Ischemic Heart DiseaseIschemiaMyocardial InfarctionCongestive Heart FailureNCT00762333UConn Health550