跳至主要内容
临床试验/NCT04192942
NCT04192942Unknown不适用

Protocol of Management of Major Pediatric Burn in Intensive Care Unit

Assiut University0 个研究点目标入组 100 人开始时间: 2019年12月最近更新:
适应症

试验速览

阶段
不适用
入组人数
100
主要终点
Changing mortality rate

研究概览

简要总结

Decrease mortality and morbidity in major pediatric burns

详细描述

The goals of initial patient management include preservation of overall homeostasis while appreciating the physiologic challenges that the burn injury poses to the body. Major burn injury not only results in local damage from the inciting injury, but in many cases results in multisystem injury. Initial efforts are focused on resuscitation, maintaining hemodynamic stability, and airway management. Intermediate efforts are focused on managing the multi-organ failure that results from systemic inflammatory mediators that result in diffuse capillary leak and surgical therapy. Finally, efforts shift to issues with chronic wound healing, pain management, restoration of functional capabilities, and rehabilitation.. Burn injury in children continues to be a major epidemiologic problem around the globe. Nearly a fourth of all burn injuries occur in children under the age of 16, of whom the majority are under the age of five This provides a team of pediatricians, surgeons, anesthesiologists, intensivists, nurses, respiratory therapists, and other healthcare providers with a unique opportunity to make a multidisciplinary collaborative effort.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
1 Year 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • age below 18 year
  • children with burn between 20% to 50% of total body surface area
  • recent burn within 48 hour

排除标准

  • old burn over 48 hour after injury -burnt surface area less than 20% of total body surface area - -
  • burnt surface area more than 50% of total body surface area
  • old age over 18 year

结局指标

主要结局

Changing mortality rate

时间窗: baseline

Change mortality rate to lowest degree which due too severe burn less than 20% of childern with major burn

次要结局

  • Changing hospital stay time(Baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed elsayed tawfik

Official investigator

Assiut University

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