Evaluation of the Soft Tissue Profile Following Socket Preservation With Platelet Rich Fibrin Versus Free Gingival Graft: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Soft tissue profile change
研究概览
简要总结
Comparing socket preservation with Platelet -Rich Fibrin versus Free gingival graft.
详细描述
Extraction of the non restorable tooth, then socket preservation is applied in experimental group using platelet rich fibrin, while in comparative group free gingival graft is applied with socket preservation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age range 25-50 years.
- •Non- restorable teeth indicated for extraction.
- •Good oral hygiene.
- •Intact facial and lingual plates of bone, without infection or pathosis.
- •Adequate apiacl bone for primaru stability
排除标准
- •Presence of uncontrolled Systemic disease eg: diabetes, bone disease or the use of medicines that interfere with bone metabolism, history of head and neck radiotherapy.
- •Presence of periodontal and/or periapical infection.
- •Non-compliant patients.
- •Pregnancy or lactation in females.
- •History of head and neck radiotherapy.
研究组 & 干预措施
Free gingival graft group
Extraction of the tooth followed by using free gingival graft to cover the socket for socket preservation.
干预措施: Free gingival graft (Other)
PRF (Platelet -rich fibrin) group
Extraction of the tooth followed by Platelet rich fibrin placed in the socket covered bu platelet rich fibrin membrane for socket preservation.
干预措施: platelet rich fibrin (Other)
结局指标
主要结局
Soft tissue profile change
时间窗: 6 months
Optical scanning by optical scanner at baseline to the preoperative cast of the related area, then optical scanning to postoperative cast of the surgical area after 6 months. Then, superimposition between the two scans of the casts will be performed to measure the difference or change in the amount of soft tissue profile measured in millimeters between baseline and at 6 months
次要结局
- Crestal bone level change(6 months)
研究者
Haya Hesham
Principle investigator
Cairo University