25gr. Glucomedics vs 25gr. Zusto
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 主要终点
- the difference in glycemic index between 25gr. Zusto® and 25gr. Glucomedics®
研究概览
简要总结
Objective: to compare blood glucose and insulin responses after consumption of 100ml water, sweetened with 25gr Zusto® and 100ml water sweetened with 25gr Glucomedics® (standard drink)
详细描述
This is an experimental study enrolling 10 healthy female subjects. The study compares the blood glucose and insulin responses after consumption of 100ml water, sweetened with 25gr Zusto® and 100ml water sweetened with 25gr Glucomedics® (standard drink). Subjects need to be fasted for at least 8 hours before all visits. At visit 1, five women will consume the solution with 25gr Zusto®, the other five will have the solution with 25gr Glucomedics®. On visit 2, groups will be switched. Visit 1 and 2 will be performed within approximately one week interval.
Both drinks will be identical in amount of water and only be different by the use of 25gr Glucomedics® and 25gr Zusto®.
Before intake of the drink, vital signs, weight and bedside blood glucose and baseline blood samples - 15' and 0' for glucose, insulin and C-peptide will be taken at visit 1 and 2. Both drinks will be consumed within 5 minutes and time of start and end of intake of Zusto® / Glucomedics® will be documented.
Blood samples for glucose, insulin and C-peptide will be taken at 15', 30', 60', 90', 120' and 180' after start of intake 25gr Zusto® and 25gr Glucomedics®.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female subjects
- •Age between 30 and 50 years
- •BMI between 20 and 30 kg/m²
排除标准
- •No first degree relatives with mellitus type 1 or type 2
- •No intake of medication with influence blood glucose levels
- •Pregnant, breast feeding or planning to become pregnant during the study
- •Employer of the investigator or study center with direct involvement in the proposed study or other studies under the direction of the investigator or study center
研究组 & 干预措施
Glucomedics®
25gr Glucomedics®
干预措施: Glucomedics® (Dietary Supplement)
Zusto®
25gr Zusto®
干预措施: Zusto (Dietary Supplement)
结局指标
主要结局
the difference in glycemic index between 25gr. Zusto® and 25gr. Glucomedics®
时间窗: 1 month
GI values will be calculated using the iAUC of Zusto® intake and Glucomedics® intake.
次要结局
未报告次要终点
研究者
Bart Keymeulen
MD PhD
AZ-VUB