跳至主要内容
临床试验/NCT05488574
NCT05488574进行中(未招募)不适用

Effects of Novel Breathing, Behavior Modification, Yoga Positioning Integrated Program on Weight Loss.

Touro University Nevada2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2022年9月20日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
80
试验地点
2
主要终点
Change rom baseline in body Weight

研究概览

简要总结

This study is to evaluate the physical and cognitive effects of a 15 min per day novel breathing and mindfulness moving-meditation program on metabolism, cognition, and emotion health. It is thought that the breathing and movement program will increase basal metabolism, facilitate fat loss, and decrease depressive behaviors. Anthropometric, blood chemistries, and cognitive measures of depression, sleep, and hunger will be measured over a two-month interventional program.

详细描述

Subjects will be randomized into two groups, an active group and control group. For the first 30 days, the active group will follow the movement/breath program and the controls will be instructed not to change their lifestyle (no change in diet, and no change in exercise / physical activities). The technicians taking measurements will be blinded as to which participants are actives vs controls. The following 30 days' intervention will consist of continuing the Phase I interventions combined with implementing the behavior change strategies on 2 to 3 habit changes self-selected from a list of 30 top "bad habits" that contribute to weight gain and undermine one's ability to lose weight with the control group again not changing any lifestyle activities. Measurements: Measurements will be taken at the start (baseline), 10 days, 30 days, and 60 days of intervention with the measurement days scheduled to evaluate people completing 10 full days of the program, 30 full days, and 60 full days respectively. Measurements taken at each interval to include weight, body composition (lean mass & fat percentages), anthropometric measurements (umbilicus, hips, right thigh, right upper arm), pO2, resting heart rate, HRV, blood pressure, pulmonary health (i.e., O2 max, spirometry), hunger, sleep, and depression rating (by self-assessment survey scale). Serum chemistry for basic metabolic panel, inflammatory markers, and lipids, hematology for oxygen carrying capacity and gross immune response, Human Growth Factor production via ELISA quantification, imaging ultrasound to measure subcutaneous fat thickness at the areas of girth measurements, DEXA for overall and targeted areas body composition, and resting metabolic rate via oxygen plethysmograph.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Investigator, Outcomes Assessor)

盲法说明

Investigators doing data collection will not know which subjects are interventional and which are controls. Outcomes assessor will not be aware of which group of subjects were interventional and which did not participate in intervention.

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • Chronic Obstructive Pulmonary Disease
  • acute respiratory distress
  • supplemental oxygen use
  • inability to stand, flex trunk, or move arms overhead
  • Pacemaker implant
  • Taking beta blocking medications.

结局指标

主要结局

Change rom baseline in body Weight

时间窗: Baseline, 10 days, 30 days, and 60 days.

Weight in kilograms

Change from baseline in Body Mass Index

时间窗: Baseline, 10 days, 30 days, and 60 days.

DEXA Measurement of % total fat

次要结局

  • Human Growth Hormone - Metabolic rate(baseline, 10 days, 30 days, 60 days)
  • lipid panel - metabolic rate(Baseline, 10 days, 30 days, and 60 days.)
  • VO2 at rest, Oxygen consumption at rest-resting metabolic rate(RMR)(Baseline, 10 days, 30 days, and 60 days.)
  • Respiratory quotient (RQ) - metabolic rate(Baseline, 10 days, 30 days, and 60 days.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Michael Laymon

Professor, Director Human Performance Laboratory

Touro University Nevada

研究点 (2)

Loading locations...

相似试验