A Randomized Controlled Trial Comparing the Segmental Artery Clamping and Main Renal Artery Clamping During Laparoscopic Partial Nephrectomy
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Glomerular Filtration Rate
研究概览
简要总结
The purpose of this study is to compare the efficacy and safety of the segmental artery clamping and main renal artery clamping during laparoscopic partial nephrectomy
详细描述
Renal tumor patients,for whom laparoscopic partial nephrectomy is suitable, will be randomly divided into two groups,segmental artery clamping group and main artery clamping group. All procedures were performed by the same laparoscopic surgeon. Blood loss, operation time, warm ischemia time, complications and affected renal function before and after operation will be recorded and compared. The safety and efficiency of laparoscopic partial nephrectomy with segmental renal artery clamping will be evaluated in comparison with the conventional main renal artery clamping technique.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •20<age<70yr
- •Stage T1a
- •Patients volunteered for this study and provided written informed consent
排除标准
- •Bilateral renal tumor
- •tumor of solitary kidney
- •glomerulonephritis
- •renal insufficiency
- •GFR of invalid kidney less than 30ml/min
- •presence of suspect metastasis
- •serious systematic disease: severe coagulation disorders
- •important organ insufficiency and severe psychological disease
研究组 & 干预措施
Segmental artery clamping
Patients with Renal tumor are randomized into this group,they will received laparoscopic partial nephrectomy. During operation, the technique of segmental renal artery clamping will performed.
干预措施: Segmental artery clamping (Procedure)
Main renal artery clamping
Patients with renal tumor are randomized into this group,they will received laparoscopic partial nephrectomy. During operation, the technique of traditional main renal artery clamping will be performed.
干预措施: Main renal artery clamping (Procedure)
结局指标
主要结局
Glomerular Filtration Rate
时间窗: 3 months postoperative
次要结局
- warm ischemia time(during surgery)
研究者
Changjun Yin
Head of Urology Department
The First Affiliated Hospital with Nanjing Medical University