Paraprofessional Treatment of Depression in Vietnam
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 473
- 试验地点
- 2
- 主要终点
- Change across time (random effects slope) in depressive symptoms, as assessed by the PHQ-9 questionnaire
研究概览
简要总结
Trained para-professional health care workers will implement a stepped-care model of depression care in commune health stations in Vietnam.
详细描述
This project focuses on evaluation of a collaborative care system for treatment of depression in Vietnam. This system involves training para-professional health care workers in a stepped-care model system of depression care to be implemented in commune health stations in Vietnam.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Depression Diagnosis
排除标准
- •active psychosis, mania, substance abuse, suicidal behaviors, cognitive impairment.
研究组 & 干预措施
Guideline Antidepressant Medication
Guideline Antidepressant Medication, following the VN National Mental Health plan.
干预措施: Guideline Antidepressant Medication (Drug)
Behavioral Activation + Medication
Psychoeducation, behavioral activation therapy, and medication delivered within a collaborative care model.
干预措施: Behavioral Activation + Medication (Other)
结局指标
主要结局
Change across time (random effects slope) in depressive symptoms, as assessed by the PHQ-9 questionnaire
时间窗: 0, 6, 12, 24 weeks
The PHQ-9 (Patient Health Questionnaire-9) assesses depressive symptoms, over the last two weeks. It is assessed at 0, 6, 12, 24 weeks. The outcome target is the linear and quadratic change slopes across these 4 time points.
次要结局
- "Depression remission", as assessed by the PHQ-9(6, 12, 24 weeks)
- "Substantial improvement" in depressive symptoms, as assessed by the PHQ-9(6, 12, 24 weeks)
- Change across time (random effects slope) in anxiety symptoms, as assessed by the GAD-7 questionnaire(0, 6, 12, 24 weeks)
- Change across time (random effects slope) in physical health, as assessed by the SF-12 questionnaire, Physical Health subscale(0, 6, 12, 24 weeks)
- Change across time (random effects slope) in behavioral activation skills and behaviors, as assessed by the BADS questionnaire.(0, 6, 12, 24 weeks)
- Change across time (random effects slope) in mental health, as assessed by the SF-12 questionnaire, Mental Health subscale(0, 6, 12, 24 weeks)
研究者
Bahr Weiss
Associate Professor
Vanderbilt University