Developing Fast Pediatric Imaging
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 6
- 主要终点
- Wave-CAIPI validation
研究概览
简要总结
This research study is evaluating the investigational software for magnetic resonance imaging (MRI) systems and techniques to process magnetic resonance (MR) images
详细描述
The purpose of the study is to develop new technologies for MRI systems. The new technologies should improve MRI capabilities in terms of how sensitive, specific, and efficient they are. The overall goal is to get better measurements of the brain tumor tissue(s).
In this research study, the investigators want to learn more about investigational software and about techniques to process MR images. The testing of investigational software will allow the investigators to improve the image quality. As part of the testing process, the investigators will collect more MR images of the brain, and improve current image reconstruction methods. This will allow a more precise analysis of MR images and potentially better assessment of the brain tumor tissue volume.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 0 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Infants, children and adults who have been diagnosed with Low Grade Glioma
- •Healthy volunteers - Children from age 0 to adults with no upper age limit or;
- •Diagnosed with LGG and being treated at DFCI;
排除标准
- •Electrical implants such as cardiac pacemakers or perfusion pumps;
- •Ferromagnetic implants such as aneurysm clips, surgical clips, prosthesis, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants;
- •Ferromagnetic objects such as jewelry or metal clips;
- •Women of childbearing age who are seeking to become pregnant, who are breastfeeding, or who suspect they may be pregnant;
- •Pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions;
- •Any greater than normal potential for cardiac arrest
结局指标
主要结局
Wave-CAIPI validation
时间窗: 2 years
The outcome measure for this project will be that the rapid scan from Wave-CAIPI can provide equivalent diagnostic quality to that of standard clinical acquisitions which is performed at much slower speed. This will be assess using visual qualitative assessment by experienced radiologists on the project.
次要结局
未报告次要终点
研究者
Ellen Grant
Principal Investigator
Boston Children's Hospital