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临床试验/NCT01553370
NCT01553370Unknown不适用

Randomized Controlled Trial of Milk Products and Physical Activity on Body Composition and Health in Overweight Young Males

Brock University2 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2012年4月最近更新:
适应症

试验速览

阶段
不适用
入组人数
54
试验地点
2
主要终点
Body composition

研究概览

简要总结

Maintaining a healthy body weight is a major challenge for the majority of Canadians. A lifestyle strategy that promotes maintenance of a healthy body weight and, perhaps most importantly, can be incorporated into daily life with relative ease is essential. This study will determine if an effective strategy includes increased physical activity in conjunction with higher intakes of dairy products immediately following exercise. Fifty-six overweight adult males who do not regularly exercise will be assigned to one of four groups for 12 weeks. All groups will preform 12 weeks of exercise training (1 hour of cycling per day, 5 times per week). Two groups will consume supplemental low fat milk (3 servings per day) with one these groups consuming it immediately after exercise while the other will consume it either well before or long after the exercise session. The other two groups will consume a carbohydrate drink that has the same amount of energy as the low fat milk, with one of these groups consuming the drink right after exercise and the other another group will consume it either well before or long after the exercise session. Markers of health status including body weight, muscle mass, and bone mass will be measured at the start and after the 12- week intervention. The investigators anticipate that providing the low fat milk immediately after exercise will result in the most favorable changes in health outcomes, and provide a realistic lifestyle intervention for overweight individuals to attain a healthy body weight, and by doing so, optimize their ability to prevent chronic disease.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 28 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • BMI greater or equal to 25

排除标准

  • any chronic cardiovascular condition or metabolic condition
  • kidney disease
  • gastro-intestinal disease
  • milk or dairy protein allergies
  • lactose intolerance
  • chronic lung conditions
  • any condition that could potentially prevent participant from performing exercise
  • allergy to local anaesthetics
  • cumulative x-ray exposure and cumulative muscle biopsies

结局指标

主要结局

Body composition

时间窗: 12 weeks

Bone mineral density

时间窗: 12 weeks

VO2 peak

时间窗: 12 weeks

次要结局

  • mitochondrial enzyme activity(12 weeks)
  • muscle oxidative stress(12 weeks)
  • muscle capillary density(12 weeks)
  • blood lipids(12 weeks)
  • blood inflammatory markers(12 weeks)
  • blood markers of bone turnover(12 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Brian Roy

Associate Professor

Brock University

研究点 (2)

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