Randomized Controlled Trial of Milk Products and Physical Activity on Body Composition and Health in Overweight Young Males
试验速览
- 阶段
- 不适用
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- Body composition
研究概览
简要总结
Maintaining a healthy body weight is a major challenge for the majority of Canadians. A lifestyle strategy that promotes maintenance of a healthy body weight and, perhaps most importantly, can be incorporated into daily life with relative ease is essential. This study will determine if an effective strategy includes increased physical activity in conjunction with higher intakes of dairy products immediately following exercise. Fifty-six overweight adult males who do not regularly exercise will be assigned to one of four groups for 12 weeks. All groups will preform 12 weeks of exercise training (1 hour of cycling per day, 5 times per week). Two groups will consume supplemental low fat milk (3 servings per day) with one these groups consuming it immediately after exercise while the other will consume it either well before or long after the exercise session. The other two groups will consume a carbohydrate drink that has the same amount of energy as the low fat milk, with one of these groups consuming the drink right after exercise and the other another group will consume it either well before or long after the exercise session. Markers of health status including body weight, muscle mass, and bone mass will be measured at the start and after the 12- week intervention. The investigators anticipate that providing the low fat milk immediately after exercise will result in the most favorable changes in health outcomes, and provide a realistic lifestyle intervention for overweight individuals to attain a healthy body weight, and by doing so, optimize their ability to prevent chronic disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 28 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI greater or equal to 25
排除标准
- •any chronic cardiovascular condition or metabolic condition
- •kidney disease
- •gastro-intestinal disease
- •milk or dairy protein allergies
- •lactose intolerance
- •chronic lung conditions
- •any condition that could potentially prevent participant from performing exercise
- •allergy to local anaesthetics
- •cumulative x-ray exposure and cumulative muscle biopsies
结局指标
主要结局
Body composition
时间窗: 12 weeks
Bone mineral density
时间窗: 12 weeks
VO2 peak
时间窗: 12 weeks
次要结局
- mitochondrial enzyme activity(12 weeks)
- muscle oxidative stress(12 weeks)
- muscle capillary density(12 weeks)
- blood lipids(12 weeks)
- blood inflammatory markers(12 weeks)
- blood markers of bone turnover(12 weeks)
研究者
Brian Roy
Associate Professor
Brock University
