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临床试验/NCT04127240
NCT04127240已完成不适用

The Effect of Meat Intake as a Part of the DASH Diet on Indices of Muscular Fitness, Body Composition and Metabolic Health in Adults 65 and Older: A Controlled-Feeding Systems-Biology Study

South Dakota State University2 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2017年6月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
46
试验地点
2
主要终点
Body weight

研究概览

简要总结

Age-related changes in body composition, muscular fitness, and metabolic health resulting in the onset of obesity, sarcopenia, and chronic diseases are profound public health issues that are in need of immediate attention. Effective and feasible methods, such as dietary therapies, are needed to improve health in older adults that in turn lead to independence, enhanced quality of life and reduced hospitalizations. Diet quality and dietary protein intake are vital for maintaining body composition, muscle mass and improved physical performance. Malnutrition in dietary protein intake is a major cause of reduced muscle mass, strength, and function in older adults. The Dietary Approaches to Stop Hypertension (DASH) dietary pattern is a high-quality therapeutic diet known to improve health status in various diverse and at-risk populations resulting in improved heart health, maintained cognitive function and reductions in metabolic diseases such as diabetes, metabolic syndrome, and nonalcoholic fatty liver disease. The primary protein recommendations of the DASH diet are poultry and fish and it is recommended to decrease or exclude red meats from the diet. However, studies have demonstrated that lean red meat incorporated into a DASH-like diet doesn't exacerbate cardiovascular health indices in adults, indicating that lean red meat can be included in the DASH diet without negative effects on heart health. Although studies have reported on the DASH diet in older adults, no studies have investigated the effect of the DASH diet containing lean red meat on measures of body composition, muscle mass or metabolic health under controlled-feeding conditions. The purpose of this study was to determine the effect of the DASH diet containing daily intakes of lean red meat on indicators of body composition, muscular fitness and biomarkers of metabolic health in adults 65 and older using controlled-feeding and systems biology approaches.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • 65 and older
  • Upward mobile ability

排除标准

  • Under the age of 65
  • Immobility

研究组 & 干预措施

Meat assignment in DASH intervention

Experimental

Participants consumed 3 ounces of red meat per day as a part of the DASH diet.

干预措施: DASH diet containing daily intakes of red meat (Other)

Meat allocation in DASH intervention

Experimental

Participants consumed 6 ounces of red meat per day as a part of the DASH diet.

干预措施: DASH diet containing daily intakes of red meat (Other)

结局指标

主要结局

Body weight

时间窗: Change in body weight from baseline to 3 months

Measured by bioelectrical impedance

Hand grip strength

时间窗: Change in strength from baseline to 3 months

Measured by a hand-held dynamometer

Glucose

时间窗: Change in glucose concentrations from baseline to 3 months

Measure serum glucose using colorimetry assay

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Cydne Perry

Assistant Professor

South Dakota State University

研究点 (2)

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