ACTRN12612000183886已完成4 期
Efficacy and safety of dihydroartemisinin-piperaquine (DP) in Pailin, Preah Vihear and Rattanakiri, and artesunate-mefloquine (ASMQ) in Preah Vihear for uncomplicated P. falciparum malaria and chloroquine (CQ) for P.vivax malaria in the above 3 sites, Cambodia, 2009
Institude Paster du Cambodge0 个研究点目标入组 420 人开始时间: 2012年2月10日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 420
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 1 Years 至 o limit（—）
- 性别
- All
入选标准
- •Above 1 year old;
- •-Mono Infection with P. falciparum or P. vivax;
- •-Parasitaemia, 1000–200 000 asexual forms per microlitre for P.f and above 250 asexual forms per microlitre for P.v ;
- •-Axillary temperature greater than 37.5 degree C
- •-Ability to swallow oral medication;
- •-Ability and willingness to comply with the study protocol for the duration of the study and to comply with the study visit schedule;
- •-Informed consent from the patient or from a parent or guardian in case of children.
排除标准
- •-Presence of general danger signs among children <5 years old or other signs of severe and complicated falciparum malaria according to current WHO definitions;
- •-Mixed species;
- •-Presence of febrile conditions due to diseases other than malaria (measles, acute lower tract respiratory infection, severe diarrhea with dehydration, etc.),
- •-Known hypersensitivity or allergy to artesunate or mefloquine
- •-Known psychiatric disorders, e.g. depression or epilepsy
- •-Anti arrhythmic or others drugs which are known to influence cardiac function
研究者
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