ISRCTN56366401已完成未知
Platelet Responsiveness and Outcome from Platelet Transfusion - does inherent variation in donor platelet function affect the clinical efficacy of apheresis platelets? A randomised double blind single centre trial.
HS Blood and Transplant [NHSBT] (UK)0 个研究点目标入组 130 人开始时间: 2012年11月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 130
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age 16 years or older
- •2. Stable Haematology/Oncology Patients at Addenbrooke?s Hospital
- •3. Thrombocytopenia secondary to bone marrow failure, requiring platelet transfusions according to local and British Committee for Standards in Haematology (BCSH) Guidelines
- •4. Patients who, if peripheral venous access for blood sampling is required, have adequate access and will consent to their blood being taken in this way
- •5. Patients able to give written informed consent
- •6. Male or female
排除标准
- •1. Inherited or acquired clotting disorders
- •2. Inherited or acquired platelet function disorders
- •3. Current Acute Promyelocytic Leukaemia
- •4. Previously documented WHO Grade 4 bleeding (debilitating blood loss)
- •5. Palpable Splenomegaly
- •6. Immunological refractoriness to platelet transfusion
- •7. Require HLA or HPA matched platelets
- •8. Pregnant or lactating women
- •9. Other active malignancy in past 5 years
研究者
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