NCT01694550已完成不适用
Corrected QT Interval in Patients With Pacemaker Dependency (QT-TENDENCY-Study)
University of Magdeburg1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2012年3月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Corrected QT Interval in Patients With Pacemaker Dependency
研究概览
简要总结
The aim of this study is to examine a correction term for an adapted QT interval during ventricular pacing (right, left and biventricular pacing) to obtain valid formulae correcting for the QT intervals in various pacing conditions.
详细描述
This investigation aims at determining a possibility to assess the usefulness of various formulae that correct for the different effects of various pacing modes on the QT interval. More specifically, the hypothesis will be tested that applying adequate correction will preserve the predictive power of the QT-interval regarding proarrhythmia in various cardiac pathologies and therapies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •caucasian race
- •implanted cardioverter/defibrillator or pacemaker
- •negative pregnancy test for women of child bearing potential
- •stable function of the implanted device
- •stable medical therapy relating to the underlying disease
- •stable medical therapy of antiarrhythmic drugs and other QT-time changing drugs
- •no instability of rhythm
- •x-ray of thorax during device implantation in two levels (ap and ll axis)
- •written informed consent
排除标准
- •coronary heart disease and angina pectoris symptoms
- •patient with acute myocardial infarction or CABG while the last 4 weeks
- •patient with tachycardia and a rest frequency >80 bpm
- •patient with severe pulmonary disease
- •patient with anaemia
- •patient with acute infections
- •patient with severe kidney or liver disease
结局指标
主要结局
Corrected QT Interval in Patients With Pacemaker Dependency
时间窗: baseline
次要结局
未报告次要终点
研究者
Dr. Samir Said
Dr. med.
University of Magdeburg
研究点 (1)
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