Influence of Post-exercise Greek Yogurt on 24 h Glycemic Control in Women With Overweight/Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Postprandial glycemia
研究概览
简要总结
The purpose of this study is to assess whether post-exercise Greek yogurt following a single session of aerobic exercise improves metabolic and musculoskeletal health in women with overweight/obesity.
详细描述
Following the acquisition of informed consent, eligibility to participate in the study will be determined using questionnaires. Participants will undergo baseline testing at our laboratory at the University of Toronto to determine cardiorespiratory fitness, body composition and undergo exercise familiarization.
Eligible participants will be assigned, in a random order, to two metabolic trials approximately 4 weeks apart that involve 4 days of controlled diet and exercise. Each trial takes place over 4 days, but participants are not required to come to the laboratory on all days. The two trials involve: 1) Exercise + Greek Yogurt (GY) 2) Exercise + a carbohydrate-based study supplement (SS).
During the 4 day trials, participants consume controlled diets and the study supplements (GY and SS). On 1 of these days participants will perform exercise in our lab followed by the consumption of GY or SS. Various outcomes will be measured throughout the trial, including glycemic control (via continuous glucose monitoring), fat oxidation, appetite and health outcomes in blood samples.
Throughout the duration of the study, participants will be asked to maintain their habitual diet and physical activity patterns, and maintain their current body weight.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •18-45 yrs
- •BMI ≥27 kg/m2
- •Elevated waist circumference (≥88 cm)
- •≤2 structured exercise sessions/week
- •Weight stable (within ± 2kg for at least 6 months)
- •Experiencing regular natural menstrual cycles
- •Non-smoker
排除标准
- •Allergy to dairy foods
- •Diagnosed lactose intolerance or an aversion to foods provided during the study (e.g., post-exercise snacks)
- •Previous history of cardiovascular or metabolic disease
- •The use of medication for managing blood glucose or lipid metabolism
- •Current use of oral contraceptives or use within the last 3 months
- •Irregular menstrual cycles (<21 days or >35 days)
- •Pregnant or lactating
- •Recreational tobacco or cannabis use
- •Inability to perform the study exercise protocols
- •Actively engaging in a low-carbohydrate diet (e.g., ketogenic, Atkins).
结局指标
主要结局
Postprandial glycemia
时间窗: 24 hour post-exercise
Postprandial glucose exposure assessed using continuous glucose monitoring
次要结局
- Fasting insulin resistance(24 hours post-exercise)
- Glycemic variability(24 hours)
- 24 hours average glucose(24 hours post-exercise)
- Post-exercise fat oxidation(1, 2 and 3 hours post-exercise)
- Fasting insulin concentration(24 hours post-exercise)
- Fasting glucose concentration(24 hours post-exercise)
- Bone metabolism(30, 90, and 180 minutes and 24 hours post-exercise)
- Nocturnal glucose(6-8 hours)
研究者
Jenna Gillen
Assistant Professor
University of Toronto