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临床试验/NCT02918565
NCT02918565已完成不适用

Mechanisms for Alcohol Treatment Change [MATCH] Study

University of Pittsburgh2 个研究点 分布在 1 个国家目标入组 1,131 人开始时间: 2016年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,131
试验地点
2
主要终点
Number of Binge Drinking Days

研究概览

简要总结

A 5-arm randomized trial to determine what components of a text message intervention are necessary to reduce hazardous drinking among young adults and mechanisms through which these changes occur.

详细描述

Young adults ages 18-25 have high rates of hazardous alcohol use and alcohol-related consequences. The Emergency Department (ED) provides an important opportunity to identify young adult hazardous drinkers who could benefit from interventions. A Text Message (TM) intervention was shown to reduce alcohol consumption among young adult ED patients, showing durable effects over 9-months. The TM intervention uses behavior change techniques with the largest effect sizes in an alcohol intervention meta-analysis: "goal commitment" and "self-monitoring", along with real-time "feedback". However, the unique effect of these ingredients, and mechanisms (processes occurring within the individual) through which they operate to reduce drinking remain unclear, a critical gap addressed by this project. Young adult ED patients (ages 18-25) who screen positive for hazardous drinking will be recruited to participate in a randomized trial to determine how best to help individuals reduce hazardous drinking. All participants will be asked to complete web-based surveys at baseline, 12 and 24 weeks after enrollment, complete brief psychomotor tasks weekly for 14 weeks, and respond to text messages each Thursday and Sunday for the next 12 weeks. Those randomized to the TM interventions will additionally receive feedback on their text reports. The four TM intervention arms are: (1) Drinking Cognition Feedback (DCF), (2) Alcohol Risk Feedback (ARF), (3) Adaptive Goal Support (AGS) and (4) a combination of DCF, ARF, and AGS=COMBO). Study results have implications for designing efficient mobile interventions, and developing a dynamic theory of behavior change.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 25 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • total score of >2 for women or >3 for men on the AUDIT-C
  • at least 1 binged drinking episode in the prior 30 days

排除标准

  • no cell phone with text messaging
  • have been diagnosed with an alcohol or substance use disorder
  • pregnant or planning pregnancy
  • taking medicine for a psychiatric disorder (including depression, anxiety)
  • taking any medicine that could interact with alcohol

结局指标

主要结局

Number of Binge Drinking Days

时间窗: 12 weeks after starting intervention

Measured by the # days on the Timeline Followback Calendar that a male reported 5+ drinks or a female reported 4+ drinks

次要结局

  • Brief Young Adult Alcohol Consequences Questionnaire Score(12 weeks after starting intervention)
  • Count of Participants With Any Binge Drinking Day(12 weeks after starting intervention)
  • Drinks Per Drinking Day(12 weeks after starting intervention)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Maria Pacella

Research Assistant Professor

University of Pittsburgh

研究点 (2)

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