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临床试验/CTRI/2025/08/093808
CTRI/2025/08/093808尚未招募不适用

EVALUATION OF PRE- OPERATIVE ULTRASONOGRAPHIC DYNAMIC VENOUS AND ARTERIAL INDICES FOR PREDICTION OF POST INDUCTION HYPOTENSION IN HYPERTENSIVE PATIENTS: AN OBSERVATIONAL STUDY

Maulana Azad Medical College1 个研究点 分布在 1 个国家目标入组 113 人开始时间: 2025年9月10日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
113
试验地点
1
主要终点
Sensitivity and specificity of dynamic indices of internal jugular vein, carotid artery and radial artery for prediction of post induction hypotension in hypertensive patients.

研究概览

简要总结

Post-induction hypotension is a common and potentially serious complication of general anesthesia, particularly in hypertensive patients who are more vulnerable due to impaired autonomic regulation, increased sympathetic tone, and vascular stiffness. Ultrasound-derived indices of  internal jugular vein, carotid artery and radial artery are emerging as valuable tools for predicting post induction hypotension. This study aims to evaluate the internal jugular vein indices, carotid artery and radial artery indices as predictors of post induction hypotension in hypertensive patients undergoing elective surgery. All patients will receive general anesthesia under a standardized protocol. Ultrasound assessments of the internal jugular vein, radial artery and carotid artery will be conducted preoperatively. Post-anesthesia, patients will be monitored for post induction hypotension. This study seeks to validate these bedside tools to help anesthesiologists better anticipate and manage post-induction hypotension in hypertensive patients.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • American society of Anesthesiologists (ASA) physical status class of II and III.

排除标准

  • 1.Poorly controlled hypertension (SBP more than 180mmHg and DBP more than 110mmHg before the day of surgery).
  • 2.Baseline systolic arterial pressure more than 180 mmHg or less than 90mmHg on the day of surgery.
  • 3.Secondary hypertension, severe cardiovascular disease (left ventricular ejection fraction less than 40%), severe congenital or valvular heart disease, cardiomyopathy, implanted pacemaker, cardioverter/defibrillator, carotid artery disease, arrhythmia, heart failure, cerebrovascular disease, peripheral vascular disease 4.BMI more than or equal to 35kg/m2 5.Suspected difficult airway, chronic obstructive pulmonary disorder, chronic renal failure or increased intra abdominal pressure.
  • 6.Pregnant or breastfeeding females.
  • 7.Patients with any history of neck or forearm surgery or trauma.

结局指标

主要结局

Sensitivity and specificity of dynamic indices of internal jugular vein, carotid artery and radial artery for prediction of post induction hypotension in hypertensive patients.

时间窗: At the end of study at the time of statistical analysis

次要结局

  • 1. Association of clinico-demographic parameters with post induction hypotension in(hypertensive patients.)
  • 2. Correlation of pre-operative ultrasonographic dynamic indices of internal jugular vein, carotid and radial(artery with percentage decrease in MAP and number of hypotensive episodes.)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Kartik Raj

Maulana Azad Medical College

研究点 (1)

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