Assessment of likelihood ratio of four characteristic Symptoms of Rhus toxicodendron of Musculoskeletal Disorders (MSD)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,200
- 试验地点
- 3
- 主要终点
- The Likelihood ratio of four symptoms of Rhus toxicodendron as mentioned will be estimated as per the patient-rated outcomes through ORIDL Scales and MYMOP-2.
研究概览
简要总结
It is a prospective, observational, open label patient outcome study for patients suffering from Musculoskeletal Disorders entitled “Assessment of likelihood ratio of four characteristic Symptoms of Rhus toxicodendron of Musculoskeletal Disorders (MSD)â€. The reliability of homeopathic prescriptions may increase through resource to characteristic signs and symptoms with significant positive likelihood ratio (LR) results may increase the reliability of homeopathic prescriptions. In this study we will estimate the LR for four characteristic symptoms of Rhus toxicodendron which will attribute to the homeopathic medicine Rhus tox in treatment for MSD. It is multi-centric observational assessment, will be conducted at Dr Anjali Chatterji Regional Research Institute (H), Kolkata , DDPR Central Research Institute (H), Noida and Regional Research Institute (H), Siliguri. All participants in the age group of 18 to 70 years having symptoms of any MSD will be studied. Here, LR will be assessed based on Bayesian statistics of four characteristic symptoms of Rhus toxicodendron in treatment for MSD. Here we will investigate the prevalence of four symptoms (i.e. Ailments from strains/over lifting/overstretching and over exertion 2. Pain < first movement > motion 3. Pain from warm application. 4. Great apprehension at night, cannot remain in bed) in the general patient population (all MSD) and among good responders to Rhus tox in daily homeopathic treatment and estimate LR for these four symptoms of Rhus tox. Rhus tox and Individualized Homoeopathic medicine in centesimal potencies manufactured by a licensed homoeopathic pharmaceutical company approved by the Council.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •Age between 18-70 years
- •Both sexes
- •Patients are suffering from any type of Musculoskeletal Disorders (Diagnosis is based clinically and physical examination; with or without imaging or other evidences).
- •Patients willing to give written consent for participation in the study.
- •Patients with controlled metabolic and systemic diseases.
- •Wash-out period of at least two weeks for any ongoing conventional medicines.
排除标准
- •Unwillingness of Patients to participate or to comply with the study requirements.
- •Pregnant women or lactating mother
- •Psychiatric illness
- •Self reported immunocompromised state,
- •Drug or substance abuse or dependence.
- •• Other uncontrolled or advanced pulmonary Diabetes mellitus, systemic diseases or pathologies affecting quality of life.
结局指标
主要结局
The Likelihood ratio of four symptoms of Rhus toxicodendron as mentioned will be estimated as per the patient-rated outcomes through ORIDL Scales and MYMOP-2.
时间窗: at base line, after 6 months of treatment.
次要结局
- 1. Evaluate the positive responses of Homoeopathic intervention in patient with Musculoskeletal disorders using ORIDL score & MYMOP2 score(2. Assessment of the pain intensity by NRS in patients with Musculoskeletal disorders.)
研究者
Dr Suraia Parveen
Dr Anjali Chatterji Regional Research Institute for Homoeopathy
