Impact of Diagnostic and Therapeutic Upper and Lower Gastrointestinal Endoscopic Management on Critically Ill Patients in Fayoum University Hospitals
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Diagnostic yield of urgent gastrointestinal endoscopy
研究概览
简要总结
Prospective study to evaluate the diagnostic and prognostic value of upper and lower gastrointestinal endoscopy in ICU
详细描述
Prospective study to evaluate the diagnostic and prognostic value of upper and lower gastrointestinal endoscopy in management of Critically ill patients with overt or suspected gastrointestinal bleeding as well as other indications in Critical Care Department of Fayoum University Hospitals
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Critically ill Patients with overt gastrointestinal bleeding
- •Critically ill Patients with suspected gastrointestinal bleeding manifestations as:
- •Acute and unexplained anemia
- •Sudden unexplained hemodynamic instability
- •Prolonged Ryle feeding (10 days)
- •Prolonged intubation (7 days)
- •Prolonged hospitalization with occult blood in stool
- •Prolonged administration of anticoagulants (2 weeks)
- •Prolonged PPI treatment and history of peptic ulcer
- •Critically ill Patients with other indications as:
- •Immunocompromised patients with oral candidiasis
- •Persistent unexplained vomiting
- •Dysphagia and odynophagia
- •Intractable or chronic gastro esophageal reflux disease
- •Chronic unexplained diarrhea
- •Unexplained Iron deficiency anemia in old age
- •Suspicion of malignant ulcer (peptic or colonic)
- •Cancer of unknown origin
- •Duodenal biopsy
- •Suspicion of colonic mass
排除标准
- •Patient refusal
- •Noncompliance
- •Facial trauma
- •Patient age less than 18 years old
研究组 & 干预措施
overt gastrointestinal bleeding
Critically ill Patients with overt gastrointestinal bleeding
Critically ill Patients with other indications
Critically ill Patients with other indications as:
- Immunocompromised patients with oral candidiasis
- Persistent unexplained vomiting
- Dysphagia and odynophagia
- Intractable or chronic gastro esophageal reflux disease
- Chronic unexplained diarrhea
- Unexplained Iron deficiency anemia in old age
- Suspicion of malignant ulcer (peptic or colonic)
- Cancer of unknown origin
- Duodenal biopsy
- Suspicion of colonic mass
结局指标
主要结局
Diagnostic yield of urgent gastrointestinal endoscopy
时间窗: within 24 hours of the endoscopic procedure
Percentage of critically ill patients undergoing urgent upper and/or lower gastrointestinal endoscopy in whom the procedure establishes a clinically relevant gastrointestinal diagnosis.
Therapeutic yield of urgent gastrointestinal endoscopy
时间窗: During the endoscopic procedure
Percentage of critically ill patients undergoing urgent upper and/or lower gastrointestinal endoscopy in whom an endoscopic therapeutic intervention is performed.
次要结局
- Length of ICU stay(up to 28 days)
- Morbidity(up to 28 days)
- ICU mortality(up to 28 days)
- Therapeutic intervention rate(During the endoscopic procedure.)
研究者
Hamada Ali Abd El Salam Abd El Latif
Assistant Lecturer of Critical Care Medicine
Fayoum University