Application of the Triple Stimulation Technique to Patients With CNS Disorders Including Stroke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Surface of the motor evoked potentials
研究概览
简要总结
TST (Triple stimulation technique) helps to better quantify the proportion of motor units activated by transcranial magnetic stimulation. The abnormal amplitude registered by TST is proportional to the intensity of conduction disorders. The evaluation of these disorders is more precise with this technique than with the slowing of the central conduction time (CCT).
The investigators propose to use this technique in CNS pathologies where this disorder is significant and essential, like multiple sclerosis and stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •stroke patients with hemiparesia
排除标准
- •pace maker
- •epilepsia
- •metallic neurosurgical implants
研究组 & 干预措施
Stroke patients
The patients will be submitted to a triple stimulation examination.
干预措施: Triple stimulation technique (Procedure)
Control Subjects
This group of patients did not suffer from a stroke. They will also be submitted to a triple stimulation examination.
干预措施: Triple stimulation technique (Procedure)
结局指标
主要结局
Surface of the motor evoked potentials
时间窗: during the TST (30 min)
Amplitude ratio of the TST
时间窗: during the TST (30 min)
Surface ratio of the TST
时间窗: during the TST (30 min)
TMS threshold
时间窗: during TST (30 min)
Amplitude of the motor evoked potentials
时间窗: during the TST (30 min)
次要结局
未报告次要终点
研究者
Bernard Dachy
Head of clinic
Brugmann University Hospital