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临床试验/ACTRN12615001227583
ACTRN12615001227583终止4 期

A randomised double blind study to evaluate the effectiveness of a CPP-ACP toothpaste to prevent carious lesions in at-risk six year old children.

The University of Queensland, School of Dentistry0 个研究点目标入组 600 人开始时间: 2015年11月10日最近更新:
适应症

试验速览

阶段
4 期
状态
终止
发起方
入组人数
600

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Prevention
盲法
Blinded (masking used)

入排标准

年龄范围
5 Years 至 7 Years(—)
性别
All

入选标准

  • One or more partially erupted/ erupted first molars
  • One or more DMFT/ dmft according to the WHO criteria

排除标准

  • - Children with a milk protein allergy
  • - Children with a benzoate sensitivity
  • - Children who are participating or have participated in the previous two years to other intervention studies
  • - Children using topical antimicrobials (except for fluoridated toothpaste)
  • - Children who have had systemic antibiotics use in the three months prior to baseline
  • - Children who reside in areas that have a non-fluoridated water supply
  • - Children who do not complete baseline treatment within 8 weeks
  • - Edentulous or children with less than 4 teeth
  • - Children with fixed or removable orthodontic appliances for cleft lip and palate
  • - Children with severe facial trauma

研究者

发起方
The University of Queensland, School of Dentistry

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