Effect of oral zinc supplementation on serum bilirubin level in term neonates undergoing phototherapy a double blind randomized placebo controlled trial
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
研究概览
简要总结
The thesis investigates the need of zinc in term neonates on serum bilirubin level undergoing phototherapy. prolonged exposure to phototherapy can lead to increased insensible water loss dehydration electrolytes imbalance increase stool frequency retinal toxicity interference with maternal infant bonding extended duration of hospital stay. zinc an essential trace element plays an important role in cellular metabolism and immune function it can reduce serum bilirubin levels by inhibiting enterohepatic circulation. zinc has been proposed as a useful adjunct in the management of neonatal hyperbilirubinemia hence this study is planned to evaluate the effect of oral zinc supplementation on serum bilirubin levels in term neonates undergoing phototherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 1.00 Day(s) 至 7.00 Day(s)（—）
- 性别
- All
入选标准
- •All healthy term neonates ( 38 to 42 weeks ) Age less then 7 days Total bilirubin in range ( 15 to 25 mg per dl ) Parental consent obtained.
排除标准
- •Neonates with sepis or conjugated hyperbilirubinemia or rds or cephalohematoma or birth asphyxia Pre term neonates ( less than 38 weeks ) Post term neonates ( more than 41 weeks ) Congenital anomalies Neonates already on zinc therapy.
研究者
Hinal doshi
Pacific institute of medical sciences