ACTRN12620001305910已完成未知
ß-Hydroxy-ß-Methylbutrate (HMB) supplementation and functional outcomes in multi-trauma patients: A feasibility and pilot randomised controlled trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 51
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •a.Adults, 18 years of age and older
- •b.Completed two full calendar days in ICU
- •c.The predominant reason for ICU admission was a traumatic injury
- •d.Allowed enteral/ oral nutrition at the time of randomization
- •Inclusion criteria for the muscle biopsy sub group as above.
排除标准
- •a. Death during ICU admission deemed to be inevitable
- •b. Bilateral above knee amputation
- •c. Patients assessed as requiring completely or predominantly parenteral nutrition
- •d. Pregnancy
- •e. Primary neuromuscular pathology present or strongly suspected this admission episode
- •f. Presumed transection of the spinal cord at any level
- •g. Medical decision treatment maker, participant or medical practitioner declined consent
- •h. Limited research availability over enrolment timeframe
- •I. Enrollment conflict with other research studies
- •j. Unlikely to be able to participate in long term follow up measures
- •k. Unable to obtain consent within 7 days from initial traumatic injury
- •Additional exclusion criteria for the muscle biopsy sub-group:
- •g.Not mechanically ventilated at the time of enrollment or predicted to be extubated within 48 hours of enrollment.
- •h.Present or strongly suspected disseminated cancer of any kind
- •i.Bleeding diathesis (corrected INR > 1.5 and/or APTT > 50 sec), or receiving any anticoagulant medication beyond that required for venous thromboembolism prophylaxis, or any antiplatelet drug other than low dose aspirin
研究者
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