Placebo-controlled double-blinded parallel randomized study to test the urate-lowering effect of yogurt containing Lactobacillus gasseri PA-3 in adult males with marginal hyperuricemia - A study on the effect of the yogurt containing Lactobacillus gasseri PA-3 on uric acid level.

Tsukuba International Clinical Pharmacology Clinic0 个研究点目标入组 60 人开始时间: 2016年2月17日最近更新: 2023年10月17日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 60

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

The results of the analysis after excluding the data with purine intake of over 450 mg/day have shown that serum urate of the high-concentration group was significantly lower than the placebo group at week 2 (P = 0.025), and the linear regression analysis has indicated a dose-dependent decrease of serum urate ( P = 0.046). The equivalent analysis using the data at week 8 also showed that serum urate of the high-concentration group was significantly lower than the placebo group (P = 0.031), and the linear regression analysis indicated a dose-dependent decrease of serum urate ( P = 0.021). Those data suggest that yogurt containing L. gasseri PA-3 lower serum urate.

研究设计

研究类型: Interventional

入排标准

年龄范围: 35years-old 至 ot applicable（—）
性别: Male

入选标准

未提供

排除标准

•1.Subjects with Phamacotherapy,Exercise therapy and Medical diet of hyperuricemia(gout). 2.Subjects with a history of gout or hyperuricemia. 3.Subjects with a using healthy food about hyperuricemia commonly. 4.Subjects who are judged ineligible by the principal investigator or subinvestigator.

研究者

发起方

Tsukuba International Clinical Pharmacology Clinic

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