Study in Calorimetric Room of the Energy Metabolism of Renal Impairment Patients Treated With Automated Peritoneal Dialysis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Energy expenditure measured by indirect calorimetry in a calorimetric chamber
研究概览
简要总结
The daily energy expenditure of patients treated with peritoneal dialysis could be increased compared to the general population and promote the development of a state of undernutrition. Conversely, the absorption of glucose by transperitoneal route could contribute to the occurrence of a metabolic syndrome.
The main objective is to compare DE and its variations according to the conditions (rest, sleep, meals, physical activity) in patients treated with automated DP compared to controls, in a calorimetric chamber.
详细描述
The daily energy expenditure of patients treated with peritoneal dialysis could be increased compared to the general population and promote the development of a state of undernutrition. Conversely, the absorption of glucose by transperitoneal route could contribute to the occurrence of a metabolic syndrome.
The main objective is to compare DE and its variations according to the conditions (rest, sleep, meals, physical activity) in patients treated with automated DP compared to controls, in a calorimetric chamber.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
盲法说明
No masking
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Patients Group DPA
- •Male patients
- •Aged 18 to 70 years
- •With end-stage renal disease
- •Treated by automatic peritoneal
- •Social security cover
- •Without acute events in the 3 months prior to inclusion
- •PCR < 30 mg/L
- •Written informed consent
- •Baecke activity score from 5 to 10
- •Healthy Volunteers
- •Male patients
- •Aged 18 to 70 years
- •Patients matched by lean body mass (± 2 kgs) and age (± 5 years)
- •Having a glomerular filtration rate estimated with the formula CKD-EPI creatinine > 60 mL / min / 1.73 m 2
- •PCR < 3 mg/L
- •Social security cover
- •Written informed consent
- •Baecke activity score from 5 to 10
排除标准
- •• - Female
- •Type 1 or 2 diabetes requiring a antidiabetic treatment
- •Decompensated heart failure
- •Smoking more than 5 cigarettes a day
- •Alcoholic patients, drinking more than 3 glass of alcohol a day
- •Patient Corticotherapy in progress
- •Patient with evolutive acute pathology
- •Person who has participated in another study within the last 30 days or is in period of exclusion on the National File of Healthy Volunteers
研究组 & 干预措施
Patients Group DPA
The main objective is to compare DE and its variations according to the conditions (rest, sleep, meals, physical activity) in patients treated with automated DP compared to controls, in a calorimetric chamber
干预措施: automated DP (Behavioral)
Healthy Volunteers
The main objective is to compare DE and its variations according to the conditions (rest, sleep, meals, physical activity) in patients treated with automated DP compared to controls, in a calorimetric chamber
干预措施: Calorimetric chamber (Behavioral)
结局指标
主要结局
Energy expenditure measured by indirect calorimetry in a calorimetric chamber
时间窗: at day 1
Energy expenditure measured by indirect calorimetry in a calorimetric chamber
次要结局
- Actimetry(at day 1)
- respiratory quotient (RQ)(at day1)
- HGPO(at day 1)