Diagnostic Accuracy of a Deep Learning Model (Artificial Intelligence) for Detecting Extra Root Canals in Mandibular Premolars on CBCT Images: Diagnostic Accuracy Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 272
- 主要终点
- Diagnostic Accuracy of the Deep Learning Model for Detection of Extra Root Canals in Mandibular Premolars
研究概览
简要总结
Successful endodontic treatment depends on the complete identification and management of the entire root canal system. Missed root canals are a major cause of endodontic failure, particularly in mandibular premolars, which exhibit considerable anatomical variability and may contain additional root canals that are difficult to detect using conventional diagnostic methods.
Cone Beam Computed Tomography (CBCT) provides three-dimensional visualization of root canal anatomy and has significantly improved the detection of anatomical variations. However, interpretation of CBCT images remains dependent on the experience and expertise of the clinician, leading to potential observer variability and missed diagnoses.
Recent advances in artificial intelligence (AI), particularly deep learning models based on convolutional neural networks, have shown promising results in dental image analysis and diagnostic support. AI-assisted diagnostic systems may improve the accuracy, consistency, and efficiency of CBCT interpretation by automatically identifying complex anatomical structures.
The aim of this retrospective diagnostic accuracy study is to evaluate the performance of a newly developed deep learning model for the detection of extra root canals in mandibular premolars using CBCT images. The diagnostic accuracy of the AI model will be assessed by comparing its findings with the assessments of experienced oral and maxillofacial radiologists, which will serve as the reference standard.
A total of 272 CBCT scans of mandibular premolars from Egyptian patients will be included according to predefined eligibility criteria. Diagnostic performance will be evaluated using measures including sensitivity, specificity, positive predictive value, and negative predictive value.
The findings of this study may provide evidence regarding the clinical applicability of AI-assisted diagnostic tools in endodontics and contribute to improved detection of complex root canal anatomy, reduced incidence of missed canals, and enhanced treatment outcomes.
详细描述
The goal of this observational study is to evaluate whether a deep learning artificial intelligence (AI) model can accurately detect extra root canals in mandibular premolars using Cone Beam Computed Tomography (CBCT) images in Egyptian patients. The main questions it aims to answer are:
- Can the AI model accurately detect extra root canals in mandibular premolars on CBCT scans?
- Is the diagnostic accuracy of the AI model comparable to that of experienced oral and maxillofacial radiologists? Researchers will compare the results generated by the AI model with the assessments of experienced radiologists, which will serve as the reference standard.
Participants will:
- Provide previously acquired CBCT scans that meet the study eligibility criteria.
- Have their CBCT images analyzed by the AI model.
- Have their CBCT images independently evaluated by experienced radiologists for comparison with the AI findings.
The study findings may help determine the potential role of AI-assisted diagnostic tools in improving the detection of complex root canal anatomy and supporting endodontic diagnosis
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •CBCT scans of mandibular molars of Egyptian patients aging from 18 to 65 years old
- •Small Field of view (FOV) including maximum a quadrant
- •Voxel size not larger than 2mm
- •Mandibular premolars showing complete root formation
- •Carious or non-carious teeth
- •Absence of artifacts.
排除标准
- •Mandibular first and second premolars with developmental anomalies, external or internal root resorption, root canal calcification, previous root canal treatment, post restorations, and/or root caries
- •CBCT images of sub-optimal quality or artifacts/high scatter interfering with proper assessment
结局指标
主要结局
Diagnostic Accuracy of the Deep Learning Model for Detection of Extra Root Canals in Mandibular Premolars
时间窗: During the procedure
Diagnostic accuracy of the AI model will be determined by comparison with expert radiologist assessment.
次要结局
- Sensitivity of the AI Model Specificity of the AI Model Positive Predictive Value (PPV) Negative Predictive Value (NPV)(During the procedure)
研究者
Ayah Tarek El Sayed Abudlaah
PHD Candidate, Cairo university
Cairo University