临床试验/NCT05175898

NCT05175898Unknown不适用

Treatment With Leftventricular Impella® Micro-axial Pump and Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) During Extracorporeal Cardiopulmonary Resuscitation (eCPR) on Mortality - An International Multicenter Cohort Study

Charite University, Berlin, Germany1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2022年2月最近更新: 2022年1月4日

适应症

试验速览

阶段: 不适用
发起方: Charite University, Berlin, Germany
入组人数: 60
试验地点: 1
主要终点: 30-day mortality

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.

详细描述

Left ventricular unloading with Impella® micro-axial pump has been shown to improve survival in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This study aims to investigate whether treatment with VA-ECMO and Impella ® (so called "ECMELLA") during extracorporeal cardiopulmonary resuscitation is associated with improved outcomes.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Adult patients
•Cardiac arrest
•Treatment with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (that is VA-ECMO plus left ventricular Impella® micro-axial pump)

排除标准

•Non-adult patients
•No treatment with VA-ECMO or "ECMELLA"

结局指标

主要结局

30-day mortality

时间窗: Mortality within 30 days after cardiac arrest event.

Mortality within 30 days after cardiac arrest event.

次要结局

Intensive Care Unit (ICU) length of stay(Through study completion - an average of 1 year.)
Hospital length of stay(Through study completion - an average of 1 year.)

研究者

发起方

Charite University, Berlin, Germany

申办方类型

Other

责任方

Principal Investigator

主要研究者

Carsten Skurk

Professor

Charite University, Berlin, Germany

研究点 (1)

Loading locations...

相似试验

已完成

3 期

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed GlioblastomaSmall Cell GlioblastomaGiant Cell GlioblastomaGliosarcomaGlioblastoma With Oligodendroglial ComponentGlioblastoma

NCT01480479Celldex Therapeutics745

已完成

不适用

Intra-articular Polyacrylamide Hydrogel in Knee OsteoarthritisOsteoarthritis

NCT03897686Research Centre BIOFORM144

招募中

不适用

Multicentric Clinical Investigation to Assess Safety and Performance of Lux HighAdd IOLCataract

NCT06446817Cutting Edge SAS57

终止

4 期

A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological MalignancyHematologic Neoplasms

NCT02895529Xian-Janssen Pharmaceutical Ltd.61

暂停

不适用

A prospective double-blind multi-centre trial: Laparoscopic versus open elective sigmoid resection in patients with symptomatic diverticulitis (Sigma-trial).1. Diverticulitis<br />2. sigmoid resection.

NL-OMON25115VU medical center104