NCT00489671已完成不适用
Differential Diagnosis Between Pancreatic Cancer and Chronic Pancreatitis: Value of the Detection of Urinary Cadmium
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 主要终点
- Exposure to cadmium, as measured by questionnaire data on dietary, occupational, and recreational exposure to cadmium, and by measurements of cadmium in urine
研究概览
简要总结
RATIONALE: Measuring cadmium levels in urine samples from patients with chronic pancreatitis may help doctors predict which patients may develop pancreatic cancer. It may also help the study of cancer in the future.
PURPOSE: This clinical trial is studying urine cadmium levels in predicting pancreatic cancer risk in patients with chronic pancreatitis.
详细描述
OBJECTIVES:
Primary
- Obtain urine samples and questionnaire data on cadmium exposure in patients with chronic pancreatitis.
- Analyze these data to determine risk of pancreatic cancer using urine cadmium levels.
Secondary
- Analyze these data in conjunction with data on serum CA 19-9, to determine whether urinary cadmium has clinical utility in predicting pancreatic cancer.
- Determine the sensitivity, specificity, and positive and negative predictive values for the cadmium test alone, CA 19-9 alone, and both tests together.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 120 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Exposure to cadmium, as measured by questionnaire data on dietary, occupational, and recreational exposure to cadmium, and by measurements of cadmium in urine
时间窗: day 1
Risk of pancreatic cancer as determined by urine cadmium levels
时间窗: day 1
次要结局
- Predictive value of urinary cadmium on development of pancreatic cancer(day 1)
- Predictive value of urinary cadmium alone, CA 19-9 alone, and both tests together on development of pancreatic cancer(day 1)
研究者
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