NCT00286663终止不适用
Evaluation of the Cellular Immune Response in Patients With Anti-SLA/LP- or Anti-LKM-Positive Autoimmune Hepatitis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 100
研究概览
简要总结
The purpose of the study is to determine the role special antibodies play in possibly identifying Autoimmune Hepatitis through the following:
Identify the response of specific T cells to antibodies and Monitor the response of the cells that regulate the immune system
详细描述
The object of this protocol is to characterize and monitor auto antigen-specific T cell responses in blood and liver biopsies of patients with anti-SLA/LP or anti-LKM-positive autoimmune hepatitis. The results will provide insight into the pathogenesis of autoimmune hepatitis and the monitoring of auto antigen-specific T cell reactivity in correlation to disease exacerbation and therapy.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female subjects,All ethnic groups, Over 18 years of age, anti-SLA/LP or anti-LKM-positive autoimmune hepatitis
排除标准
- •Subjects with a hematocrit of <25
研究者
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