NCT05784090招募中不适用
Livelli di Melatonina e Dei Suoi Precursori/Metaboliti in Differenti Fluidi Biologici: vi è Correlazione?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Melatonin levels in cerebrospinal fluid
研究概览
简要总结
The goal of this observational study is to evaluate and to correlate melatonin levels in plasma, saliva and cerebrospinal fluid (CSF) samples of patients undergoing lumbar puncture diagnostic for specific neurological diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neurodegenerative disease
排除标准
- •Age < 18 years
- •Pregnancy
- •Coagulations disorders
- •Anticoagulant therapy
结局指标
主要结局
Melatonin levels in cerebrospinal fluid
时间窗: Baseline
Analysis of melatonin levels by ELISA kit. Values expressed in pg/ml
Melatonin levels in plasma
时间窗: Baseline
Analysis of melatonin levels by ELISA kit. Values expressed in pg/ml
Melatonin levels in saliva
时间窗: Baseline
Analysis of melatonin levels by ELISA kit. Values expressed in pg/ml
次要结局
- Neurofilaments light chain levels (NFL) in cerebrospinal fluid(Baseline)
- Orexin levels in cerebrospinal fluid(Baseline)
研究者
研究点 (1)
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