Robotic Versus Laparoscopic Surgery for Middle and Low Rectal Cancer: A Retrospective Cohort Study Emulating the Target Trial
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,702
- 试验地点
- 1
- 主要终点
- 3-year postoperative disease-free survival rate
研究概览
简要总结
This study aims to compare the effectiveness of robotic surgery versus laparoscopic surgery in treating low rectal cancer. While robotic surgery has gained popularity, there is limited long-term evidence regarding its outcomes. By using real-world data from a specialized multicenter colorectal cancer database in Shanghai, China, this retrospective cohort study will emulate the target trial to evaluate whether robotic surgery offers advantages over laparoscopic surgery. Key factors such as disease-free survival, locoregional recurrence, circumferential margin positivity, and postoperative complications will be examined. The goal is to provide stronger, evidence-based support for the clinical use of robotic surgery in treating low rectal cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
3-year postoperative disease-free survival rate
时间窗: From surgery to three years postoperatively
Disease-free survival event is defined as any death or locoregional recurrence or distant metastases.
次要结局
- Circumferential resection margin positivity rate(14 days during postoperative pathological examination)
- 30-day postoperative complication rate (Clavien-Dindo grade 2 or higher grade)(From surgery to 30 days postoperatively)
- rate of abdominoperineal resection(30 days after surgery)
- 3-year postoperative locoregional recurrence rate(From surgery to three years postoperatively)
研究者
Xu jianmin
Director of Colorectal Surgery
Fudan University