The Impact of Inspiratory Muscle Strength Training on Weaning Parameters Among Ventilator-dependent Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 试验地点
- 2
- 主要终点
- Minute ventilation volume
研究概览
简要总结
The study is a pre-post test with quasi experimental design. Forty-two intubated-adults who had been mechanically ventilated for more than 21 days were selected on the basis of inclusion criteria in respiratory care ward. These patients were classified equally into study group and control group. The experimental group received the intervention of respiratory muscles training 5 times/ a week for 6 weeks. The control group received normal care. The intervention was adjusted trigger sensitivity to 10% of the first recorded Maximal Inspiratory Pressure at the start of training, then increased the ventilator trigger sensitivity and training duration weekly. The largest of ventilator trigger sensitivity is not over 40% of the initial Maximal Inspiratory Pressure and the timing of training duration is no longer than 30 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >20y/o
- •Vital signs stable
- •MIP <20cmH2O
- •Ventilator FiO2<40%, PEEP <8
- •Ventilator mode:PSV or SIMV
排除标准
- •Patient or family refuse
研究组 & 干预措施
Control group
as usual care
experimental group
The intervention of inspiratory muscle strength training
干预措施: inspiratory muscle strength training (Device)
结局指标
主要结局
Minute ventilation volume
时间窗: 7 weeks
the quantity of air moved into and out of the lungs in a minute, measurement by l.min
Oxygenation index.
时间窗: 7 weeks
Oxygenation index OI = FiO2 x 100 x M AP/PaO2, where FiO2 is the fraction of inspired oxygen, MAP is the mean airway pressure, and PaO2 is the partial pressure of oxygen in arterial blood, calculated at the end of the first day of standardized preoperative stabilization
Maximal inspiratory pressure
时间窗: 7 weeks
a measure of the strength of inspiratory muscles, measurement by cmH2O.
Rapid shallow breathing index
时间窗: 7 weeks
the ratio of respiratory frequency to tidal volume (f/VT)
Tidal volume
时间窗: 7 weeks
the volume of air that is transported into and out of the lungs with each respiratory cycle, measurement by mL per inspiration
次要结局
未报告次要终点
