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临床试验/NCT01864980
NCT01864980已完成不适用

Monitoring of Intraoperative Blood Loss: Benefit of Continuous Noninvasive Haemoglobin Monitoring?

University Medical Center Groningen1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2013年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
HbAUC

研究概览

简要总结

Certain types of surgery are associated with occult blood loss, which is hard to detect intraoperatively by intermittent conventional, invasive Hb concentration measurements using the clinical standard of Hb monitoring by satellite laboratory analysis (Hbsatlab). The investigators want to see whether continuous non-invasive transcutaneous Hb measurement using a finger sensor (SpHb), (a) reduces the total time (area under the curve, AUC) a patient's Hb is below a predetermined transfusion threshold (HbAUC) for administration of red blood cell concentrate (RBC), and (b) prevents a decrease in total oxygen delivery (DO2) possibly associated with transfusion below a critical haemoglobin concentration. Furthermore, the investigators want to study if SpHb monitoring changes the timing of RBC administration and reduces the need for intra- and post-operative RBC transfusion.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients at the age of 18 years or older, planned for elective surgery at-risk for undetected blood loss.
  • American Society of Anesthesiologists (ASA) classification I, II, III, IV

排除标准

  • Patient refusal
  • Emergency surgery

结局指标

主要结局

HbAUC

时间窗: during operation

the total time a patient's Hb is below a predetermined transfusion threshold (HbAUC) for administration of red blood cell concentrate

次要结局

  • blood transfusions(intra- and post operative up to 48h)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Prof.dr.T.W.L.Scheeren

Prof.dr.

University Medical Center Groningen

研究点 (1)

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