跳至主要内容
临床试验/NCT01391897
NCT01391897Unknown不适用

Epigenetics of Posttraumatic Stress Disorder and Somatoform Disorders in the Course of Psychotherapy

Hannover Medical School1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
入组人数
300
试验地点
1

研究概览

简要总结

This reported observational clinical study aims at identifying epigenetic markers in a sample of patients undergoing high dose inpatient psychotherapy suffering from a variety of psychiatric/psychosomatic diseases such as somatoform disorders, posttraumatic stress disorder (PTSD), depression, anxiety disorders and eating disorders.

The exact epigenetic markers that will be traced are yet to define.

The investigators believe that

  1. Epigenetic patterns found in the group of psychiatric patients show differences from healthy controls
  2. Different diagnosis show differences in epigenetic patterns as well
  3. Epigenetic patterns correlate to the severity of the psychosocial disorder as measured in interviews or psychometric ratings
  4. Epigenetic patterns can change under inpatient high dose psychotherapy
  5. Changes correlate to clinical psychometric variables.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •informed consent given by the patient
  • •adulthood to 65 years
  • •stabel physical health
  • •at least fluent in German language (as it is a group-therapy)

排除标准

  • •psychiatric disorder such as substance addiction, psychosis, schizophrenia.
  • •insufficient understanding of the terms and conditions of the study
  • •insufficient emotional stability to fill out the psychometric forms required for the study.

研究者

申办方类型
Other

研究点 (1)

Loading locations...

相似试验