Normal and Abnormal Event Related Potentials During Attribution of Intentions to Others and Resolution of Emotional Conflicts in Schizophrenia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Event related electric amplitudes
研究概览
简要总结
Case-control comparison of clinical population, interventional and single-center research.
详细描述
The main objective of this study is to define and characterize electrophysiological markers of the existing social cognition disorders in schizophrenia. Two groups of subjects are recorded : schizophrenic patients and healthy controls. Visual reinforcement effect during theory of mind judgment is tested.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Written informed consent French mother tongue Schizophrenia diagnosis according to DSM-IV-R for the patient group
排除标准
- •Coma history, epilepsy, head trauma with loss knowledge greater 10 min ECT older than 1 month DSM-4 R criteria of toxic addiction in the last 6 months Deafness or blindness Scalp pathology Intracranial implanted device
研究组 & 干预措施
Patients
Treated or hospitalized patients for schizophrenia.
干预措施: Theory of mind without visual cues (Behavioral)
Control
No schizophrenic participants, comparable to schizophrenia patients in age, gender, education level and socio premorbid verbal IQ.
干预措施: Theory of mind without visual cues (Behavioral)
结局指标
主要结局
Event related electric amplitudes
时间窗: Day 0
Scalp EEG recordings (microvolts) with respect to average or vertex references
次要结局
未报告次要终点
研究者
Eric BRUNET
Investigator coordinator
Versailles Hospital